# Morphology and Imaging Core

> **NIH NIH P30** · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2022 · $127,912

## Abstract

SUMMARY/ABSTRACT - MORPHOLOGY AND IMAGING CORE
The Morphology and Imaging Core provides access to expert personnel and specialized equipment for
investigating the anatomy and cell biology of both fixed and live tissues. This Core enhances the research
environment by facilitating the research activities of investigators who use anatomical and imaging techniques.
Because of the technical expertise provided, this Core enables other investigators to add anatomical and
imaging techniques to their repertoire of research tools. This Core is housed in a dedicated suite of rooms
totaling 921 sq. ft. Access and training are provided for instrumentation used in 1) processing ocular tissue for
light and confocal microscopy, transmission electron microscopy, immunohistochemistry, and in situ
hybridization, and 2) capturing and processing images from live or fixed tissues. Equipment available in this
Core includes two cryostats, a paraffin processing and embedding station and paraffin microtome, an
ultramicrotome for ultra-thin sectioning for electron microscopy, two research-grade epifluorescence
microscopes, a Leica TCS SP5 confocal microscope, a newly installed Leica Stellaris 8 Confocal Microscopy
System and a Leica laser microdissection microscope. In addition, there are computer workstations dedicated
to image analysis that run a stand-alone version of Leica AF, plus MetaMorph, Imaris and other imaging
software packages.
The Morphology and Imaging Core is staffed by a full-time technician, Mr. Brad Nelson, who processes and
sections fixed tissues, assists users with experimental methods, trains users on the epifluorescence
microscopes and the microscopes’ imaging software. Another key function of the technician is to maintain the
Core’s equipment. A second key staff person, Dr. Steve Lentz (20% effort, paid by the Department of
Ophthalmology), trains users on the confocal microscopes and the advanced features of the Leica AF,
MetaMorph, and Imaris software packages. During the next funding period, it is anticipated that 15
investigators will use this Core to a moderate or extensive degree. During the past 5 years, this Core was
moderately or extensively utilized by 14 investigators.

## Key facts

- **NIH application ID:** 10498047
- **Project number:** 2P30EY007003-36
- **Recipient organization:** UNIVERSITY OF MICHIGAN AT ANN ARBOR
- **Principal Investigator:** Peter F Hitchcock
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $127,912
- **Award type:** 2
- **Project period:** 1997-05-01 → 2027-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10498047

## Citation

> US National Institutes of Health, RePORTER application 10498047, Morphology and Imaging Core (2P30EY007003-36). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10498047. Licensed CC0.

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