# Case Comprehensive Cancer Center Support Grant

> **NIH NIH P30** · CASE WESTERN RESERVE UNIVERSITY · 2022 · $124,938

## Abstract

Title of the Project: BER Inhibitor TRC102 added to Standard Pemetrexed-Platinum-
Radiation in Stage III Non-Squamous Non-Small Cell Lung Cancer
Project Summary/Abstract
This application is being submitted to request for an administrative supplement through
the P30 CA043703-24 for the approved LOI #10512 (BER Inhibitor TRC102 added to
Standard Pemetrexed-Platinum-Radiation in Stage III Non-Squamous Non-Small Cell
Lung Cancer).
The Case Comprehensive Cancer Center (Case CCC) has a long track record in
conducting early phase clinical trials with a variety of sponsors, including pharmaceutical,
physician-investigator and CTEP sponsored studies. Seidman Cancer Center, a member
of the Case CCC, enrolls over 120 patients per year in early phase trials. It has a
significant infrastructure in place that allows for rapid study activation, patient accrual and
enrollment of patients with uncommon genomic abnormalities, minority accrual, quality
nursing, and data management. The structure of the phase I program engages
physicians from disease sub-specialties. The quality assurance program and regular
weekly staff meetings provide internal oversight. Recently the LOI# 10512 was
approved by CTEP to open a phase IIR clinical trial through ETCTN. Through the
requested administrative supplement (EDDOP), we hope to be able to open and complete
the clinical trial with CTEP.

## Key facts

- **NIH application ID:** 10498139
- **Project number:** 3P30CA043703-32S1
- **Recipient organization:** CASE WESTERN RESERVE UNIVERSITY
- **Principal Investigator:** STANTON L. GERSON
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $124,938
- **Award type:** 3
- **Project period:** 1997-08-01 → 2023-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10498139

## Citation

> US National Institutes of Health, RePORTER application 10498139, Case Comprehensive Cancer Center Support Grant (3P30CA043703-32S1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10498139. Licensed CC0.

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