# Mechanisms of heavy metal-induced disease and therapeutic strategies

> **NIH NIH UL1** · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · 2022 · $45,504

## Abstract

PARENT AWARD SUMMARY
Our vision for the University of New Mexico Health Science Center (UNM) Clinical and Translational Science
Center (CTSC) is to be an essential part of tightly integrated networks. The resulting collective synergy will
catalyze transit of therapeutic, diagnostic, and preventative interventions; disseminate innovative translational
research methods and best practices; and lead informatics standards and policy development to promote shared
resources and clinical and translational research (CTR). We will accomplish this by providing tailed resources to
accelerate translation, which will be harmonized with other CTSA hubs, including for example: multi-site study
support, regulatory support, research design, workforce training, and integrated informatics support. Our focus
will be to advance the full spectrum of both clinical and translational research and science (CTR/S). So that our
impact is clearly demonstrated, we also propose meaningful, measureable goals and outcomes. The UNM CTSC
offers a unique setting to achieve this vision and to catalyze high quality CTR/S. One of four majority-minority
states, New Mexico is ethnically diverse (Anglo, Hispanic, Native American), rural, and medically disenfranchised
with health-disparate populations. Our state presents geographic, racial/ethnic, and rural obstacles to health care
and outcomes and is among only five of 24 IDeA states with a CTSC hub. A key element of our CTSC is
continuous improvement and learning in order to translate what we know into what we do. In order to achieve
this, we will continue to build and enhance synergy among new technological capabilities, catalyze opportunities,
and effect institutional policy change. Through the following five strategic aims, we are poised to play a leadership
role in our state and region while being a significant asset to and partner in the CTSA consortium: 1) Align the
governance, leadership, and strategic planning of the entire UNM health system, its partners, and its academic
enterprise with the CTSC and CTR/S; 2) Engage in beneficial collaboration and partnerships; 3) Use our initial
success in education and training to build the translational workforce of tomorrow; 4) Develop and disseminate
innovative and streamlined research resources (including data and informatics), methods, and processes with a
focus on quality and efficiency; 5) Integrate translational science across its multiple phases and disciplines within
complex populations and across the lifespan. With our CTSC as the catalyst, our expected outcomes are to a)
improve health through continuous input, innovation, and learning; b) speed the development and use of new
diagnostics, therapeutics, preventative interventions; and c) focus on complex and special populations in our
state and region, including those that are rural, underserved, and diverse across the continuum of lifespan.
PROJECT SUMMARY
Gadolinium (Gd)-based contrast agents cause the sometimes-lethal and often ...

## Key facts

- **NIH application ID:** 10517910
- **Project number:** 3UL1TR001449-08S1
- **Recipient organization:** UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
- **Principal Investigator:** Matthew J Campen
- **Activity code:** UL1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $45,504
- **Award type:** 3
- **Project period:** 2015-08-14 → 2025-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10517910

## Citation

> US National Institutes of Health, RePORTER application 10517910, Mechanisms of heavy metal-induced disease and therapeutic strategies (3UL1TR001449-08S1). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10517910. Licensed CC0.

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