# TBEL Admin Core

> **NIH NIH U54** · UNIVERSITY OF TX MD ANDERSON CAN CTR · 2022 · $151,713

## Abstract

ADMINISTRATIVE CORE - Abstract
The Administrative Core (AC) will provide all of the administrative and communications support to the Tri-State
Pancreatic Adenocarcinoma TBEL (Tri-PACT) Center investigators, and form the central “hub” for productive
interactions within the NCI TBEL community. The title of our Tri-PACT Center proposal is “Tumor
Microenvironment Crosstalk Drives Early Lesions in Pancreatic Cancer”, and our Center incorporates three
institutions – UT MD Anderson cancer Center (UTMDACC), University of Michigan (UMich) and Johns Hopkins
University (JHU) in a collaborative and integrated U54 endeavor to study early pancreatic neoplasia. The Tri-
PACT Center AC will be led by overall Contact PI, Dr. Anirban Maitra, and Co-PI Dr. Marina Pasca di Magliano,
and housed within the Sheikh Ahmed Center for Pancreatic Cancer Research at UTMDACC. The AC will be
supported by a PhD-level Core Administrator with experience with multi-investigator grants. Further, Dr. Yu
Shen, Professor and Chair ad interim of Biostatistics at UTMDACC, will provide comprehensive statistical
support for the Tri-PACT Center and will be assisted by a senior statistical analyst. Dr. Maitra and the AC have
considerable experience in overseeing and participating in multi-investigator grants that include programmatic
NCI U01, P01 and P50 Grants. The overall goals of the AC will be (a) to monitor research progress and to
provide stable and continuous leadership that advances integration, communication, and collaboration among
the Tri-PACT Center investigators participating in the three proposed projects and shared resource core
(Multiscale Computational Oncology Research Core or M-CORE), and (b) to ensure productive interactions with
other concurrently funded TBEL U54 sites and the TBEL CDMC, through formal and informal collaborative
endeavors under the TBEL umbrella. The AC will leverage the wide-ranging research expertise of both the
Internal Advisory Board (IAB) and the External Advisory Board (EAB) in critical decision-making steps, such as
changes in research directions of currently proposed projects. The AC will ensure fiscal management, including
personnel, budgets, and effort oversight, facilitate organization of virtual and in-person work-in-progress
meetings for Tri-PACT center investigators, engage in manuscript preparation, and provide federally mandated
progress and other reports to the NCI. The AC will facilitate attendance for the PIs and Tri-PACT investigators
to the semi-annual TBEL consortium meetings, and ensure our participation in other network activities, including
TBEL working groups, trans-network collaborations, and dissemination of results within and beyond the TBEL
community. The AC will serve as a liaison with the TBEL CDMC in ensuring the transfer of TriPACT Center-
generated data and materials under appropriate transfer agreements. The AC will also ensure timely
communication and consultation with the NCI Program Directors for both adherence and...

## Key facts

- **NIH application ID:** 10518936
- **Project number:** 1U54CA274371-01
- **Recipient organization:** UNIVERSITY OF TX MD ANDERSON CAN CTR
- **Principal Investigator:** ANIRBAN MAITRA
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $151,713
- **Award type:** 1
- **Project period:** 2022-09-21 → 2027-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10518936

## Citation

> US National Institutes of Health, RePORTER application 10518936, TBEL Admin Core (1U54CA274371-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10518936. Licensed CC0.

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