# Administrative Core

> **NIH NIH P50** · DUKE UNIVERSITY · 2022 · $158,084

## Abstract

ABSTRACT – Administrative Core
The overall goal of the Duke Autism Center of Excellence (ACE) is to use a translational digital health and
computational approach to address the critical need for more effective early autism screening tools, objective
and sensitive outcome measures, and brain-based biomarkers that can be used in clinical trials with young
autistic children. We will achieve our goals by harnessing shared technologies, computational methods, and
clinical expertise across three Projects and with the support of three Cores: The Dissemination and Outreach
Core, the Data Management and Analysis Core, and the Administrative Core. The Administrative Core will serve
as the Center’s “hub”, coordinating and overseeing all Projects and Cores so they function effectively and
efficiently as a whole in an integrated and synergistic fashion. The Administrative Core will promote an inclusive,
equitable environment of communication and collaboration among investigators, reduce administrative burden
on investigators, provide financial oversight, monitor regulatory compliance, and ensure scientific rigor and
productivity. The Core will be directed by Center Director and Principal Investigator, Dr. Geraldine Dawson, who
will work closely with expert administrative staff, an internal Executive Committee, a Community Engagement
Advisory Board, and an External Advisory Committee. The Administrative Core has three specific aims. First,
the Core will coordinate communication, data-sharing, and collaboration among Center investigators to enhance
cross-Projects synergies, shared expertise and resources, and scientific progress through all phases of the
research program. Second, the Core will provide overall management and oversight of the Center. The Core will
oversee and support the Center’s scientific efforts by setting goals, defining deliverables, and monitoring
progress, ensuring timely advancement toward milestones and deliverables. Third, the Core will provide timely
financial accounting and ensure compliance with institutional, state, and federal research and ethical guidelines,
quality control, and cost-effectiveness. The Core will be responsible for providing expertise and infrastructure for
strong financial management; ensuring compliance with university, state, NIH, and other federal research
regulations; managing Institutional Review Board submissions and communication; developing and
disseminating Standard Operating Procedures; implementing Good Clinical Practice; maintaining research
fidelity; overseeing quality control; and ensuring timely submissions to the National Database for Autism
Research.

## Key facts

- **NIH application ID:** 10523404
- **Project number:** 2P50HD093074-06
- **Recipient organization:** DUKE UNIVERSITY
- **Principal Investigator:** Geraldine Dawson
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $158,084
- **Award type:** 2
- **Project period:** 2017-09-07 → 2027-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10523404

## Citation

> US National Institutes of Health, RePORTER application 10523404, Administrative Core (2P50HD093074-06). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10523404. Licensed CC0.

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