# Video repositories for clinical research: Overcoming barriers and testing utility

> **NIH NIH R21** · VIRGINIA COMMONWEALTH UNIVERSITY · 2022 · $249,575

## Abstract

Project Summary
Patient observation is a cornerstone of provider assessment. In addition, observations are often included in
clinical scoring systems, such as the Glasgow Coma Scale and the Apgar Score, which are used to classify
patients and in research as surrogate outcomes. Most observation data, however, is subject to significant
problems with inter-rater reliability, which makes them less robust compared with objective measurable data
such as blood test values. This unreliability is due in part to using limited, unrepresentative subject samples
during their creation and validation. To overcome this problem, the recommended approach is to use large data
sets from a variety of sources. This has led to the creation of data registries and biorepositories. To date, however,
there are almost no examples of repositories which curate observations via video recording. While the overall
framework for the design and management of other registries and repositories is well established, concerns
regarding privacy/security and liability risk have prevented video repository formation. The primary objective of
this study is to design solutions to these concerns and produce a guideline or manual for the creation of clinical
video repositories. The project is innovative in that very few such repositories currently exist, despite their clear
advantages for improving observational science. The first Aim is to create a roadmap for a clinical video
repository, using two sites to increase the likelihood of identifying barriers. Groups of stakeholders will be
established at each site, to include Institutional Review Board officials, health system legal/compliance officials,
and video subjects (parents of newborns for this prototype). Existing best practices guidelines will be modified
to address video related issues, and completely anonymized videos will be created using inexpensive technology.
The stakeholders will be engaged in an iterative Delphi-like process to judge the acceptability of proposed
repository regulations and the anonymized videos, finally creating a complete guidance document for video
repositories. The second Aim will be to test the utility of a prototype clinical video repository by a) inviting other
sites to participate, to ensure the generalizability of the agreement and b) establish a newborn resuscitation
video repository and use the videos to identify and then test observations made during resuscitation for their
ability to differentiate between normal and abnormal newborn transitions. These could would subsequently be
used for clinical studies to establish newborn assessment measures that are applicable to the current state of
newborn resuscitation. Having a well-accepted system to accrue and use videos for clinical research will improve
observational assessment reproducibility and open new areas of research, such as in improving telehealth
interactions.

## Key facts

- **NIH application ID:** 10523823
- **Project number:** 1R21TR003994-01A1
- **Recipient organization:** VIRGINIA COMMONWEALTH UNIVERSITY
- **Principal Investigator:** Elizabeth Foglia
- **Activity code:** R21 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $249,575
- **Award type:** 1
- **Project period:** 2022-08-01 → 2024-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10523823

## Citation

> US National Institutes of Health, RePORTER application 10523823, Video repositories for clinical research: Overcoming barriers and testing utility (1R21TR003994-01A1). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10523823. Licensed CC0.

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