PROJECT SUMMARY (30 lines): Advanced practice registered nurses and medical students, particularly those from groups underrepresented in the biomedical and behavioral sciences, need (1) robust education and research training in substance use disorders (SUDs) and (2) targeted encouragement and advanced training to promote careers in addiction research. Therefore, this R25 science education program, Increasing Minority Physician and APRN Clinician- scientist Research Training To Equalize Addiction Medicine (IMPACT TEAM), builds upon prior NIH initiatives to promote clinician-scientist research career development. We propose that to increase the pipeline of the available workforce of underrepresented nursing and medical practitioners who have research-based training in SUDs to contribute to the size and diversity of the research workforce to ultimately advance the science on the causes and consequences of substance use, we need to target outreach and engagement from these student populations early in their careers to reduce attrition from research careers. The following specific aims will enable us to attain this goal: (1) Develop and implement a rigorous outreach program recruiting members of underrepresented groups using multiple strategies and existing Michigan State University initiatives to engage these students; (2) Refine and deliver and interprofessional addiction curriculum for students; (3) actively recruit a subset of students engaged in training under Aim 2 to participate in interprofessional research collaborations geared toward launching a research career. To accomplish this, we will promote engagement through outreach programming aimed at underrepresented and disadvantaged students. We will provide the students with interprofessional curricular exposure to principles of addiction medicine practice and research. Lastly, we will leverage existing university resources and collaboratives to create a robust mentor group consisting of accomplished NIH-funded researchers from many backgrounds to support students through early-preprofessional research. Our mentors will assist students in exploring SUD research through a publication/presentation disseminating SUD research. Through this program, we will assist students' exploration of research through mentored research projects to engage them early in their education. This effort will promote a pipeline of advanced practice registered nurses and physician clinician-scientists from underrepresented and disadvantaged backgrounds poised to be future leaders in providing SUD healthcare and conducting research to implement and disseminate evidence-based SUD care.