# Outreach Core

> **NIH NIH U54** · INSTITUTE FOR SYSTEMS BIOLOGY · 2022 · $148,888

## Abstract

Outreach. Project Summary.
The ST-Analytics scientific program is designed to take a systems biology approach towards addressing the
question of how to effectively administer targeted-inhibitor – immunotherapy sequential combinations for the
treatment of solid tumors, with an emphasis on melanoma. ST Analytics incorporates state-of-the-art
experimental and computational programs advancing in close feedback with each other towards a robust
solution. The ST-Analytics Outreach Program is designed as a highly complementary program, with STEM
outreach goals that are aligned with the core scientific theme of the U54. The Outreach program takes advantage
of ISB’s ‘Systems Education Experiences’ teacher Educational Programs that promote systems approaches to
scientific problem solving through the development of educational modules that have provided positive STEM
learning experiences for millions of students worldwide, and in each of the 50 states. A strong emphasis is
placed on providing systems immuno-oncology internships and experiences to student populations traditionally
under-represented in the STEM fields. The basic approach is to integrate these interns with ST-Analytics
researchers to incorporate systems immuno-oncology concepts into two existing or in-development educational
modules, entitled Systems Medicine Module 3 - Personalizing Disease Treatments, and Gaining Insight through
Systems Thinking and Computational Modeling. While those modules are designed to meet Next Generation
Science Standards (NGSS), the professional educators who are tasked with implementing those standards often
do not have the proper background or supporting materials for the job. Thus, our outreach programs are also
designed to provide that background and support. For example, we provide research-based, reality-driven
professional development for more than 1,000 teachers and 80 district administrators annually, impacting over
two-thirds of students in Washington. Thus, the potential impact of an ST-Analytics outreach program is large,
and is achieved by leveraging extensive existing resources and relationships that extend throughout the state of
WA and up and down the U.S. west coast. A program that solicits creative engagement from all participants
within our proposed U54 program at all levels is described.

## Key facts

- **NIH application ID:** 10526105
- **Project number:** 1U54CA274509-01
- **Recipient organization:** INSTITUTE FOR SYSTEMS BIOLOGY
- **Principal Investigator:** Claudia Ludwig
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $148,888
- **Award type:** 1
- **Project period:** 2022-09-22 → 2027-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10526105

## Citation

> US National Institutes of Health, RePORTER application 10526105, Outreach Core (1U54CA274509-01). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10526105. Licensed CC0.

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