# Combining mHealth and nurse-delivered care to improve the outcomes of people with seriousmental illness in West Africa

> **NIH NIH R01** · UNIVERSITY OF WASHINGTON · 2022 · $696,049

## Abstract

PROJECT SUMMARY
 Worldwide, serious mental illnesses (SMI) such as schizophrenia or bipolar disorder are major causes of
impairment and disability. In West Africa, the hardships of SMI are compounded by pervasive societal stigma,
scarce treatment options, systematic exclusion, neglect, and abuse. People with SMI in West Africa describe
the experience as akin to “receiving a death sentence.” West African mental healthcare systems have severely
constrained resources that contribute to a large treatment gap. Most people with SMI receive services from
traditional and faith healers who do not provide high quality care. Healers often use practices such as chaining,
seclusion, and forced fasting that often worsen the negative impacts of SMI. Given the shortage of skilled
mental health providers and the prevalence of healers, coupled with the established infrastructure healers have
in place (e.g., referral networks, “prayer camps”, community ties) global health leaders have argued that
healers and prayer camp settings may be leveraged as conduits for treatment, provided they receive
appropriate training and support to provide higher quality care. Our multinational research team has developed
M&M: a dual-pronged intervention package comprised of a mobile health program designed to train healers to
deliver evidence-based psychosocial interventions while maintaining safety and patient dignity in practice (M-
Healer) combined with pharmacotherapy delivered directly to the patients at their prayer camps via visiting
nurse (Mobile Nurse). We have successfully completed usability, acceptability, feasibility and preliminary
clinical testing of the modular elements of the intervention at prayer camps, with very promising results. We
now propose to evaluate the effectiveness of the integrated M&M intervention in a fully-powered trial and share
it widely through a new West African Digital Mental Health Alliance (WADMA), a mission centered network
designed to jumpstart digital mental health research and cross institutional collaboration though grant funded
studies, education, and integration of digital mental health tools in clinical practice. We aim to: 1. Evaluate the
effectiveness of the M&M intervention using a stepped-wedge cluster randomized trial design; 2. Examine
mediators and moderators of M&M intervention effects; and 3. Use qualitative methods to inform M&M
intervention optimization and future implementation. Although focused on West Africa, the dual-pronged model
we are testing to address quality of care needs, the outcomes we will measure, and the methodological
lessons we will learn will all have translational implications for development and implementation of integrated
technology-assisted treatment support packages for paraprofessionals caring for people with SMI in the United
States.

## Key facts

- **NIH application ID:** 10533529
- **Project number:** 1R01MH127531-01A1
- **Recipient organization:** UNIVERSITY OF WASHINGTON
- **Principal Investigator:** Dror Ben-Zeev
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $696,049
- **Award type:** 1
- **Project period:** 2022-08-05 → 2027-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10533529

## Citation

> US National Institutes of Health, RePORTER application 10533529, Combining mHealth and nurse-delivered care to improve the outcomes of people with seriousmental illness in West Africa (1R01MH127531-01A1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10533529. Licensed CC0.

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