# Planning for Prevention of Parkinson's disease: A Trial Design Forum

> **NIH NIH R13** · MASSACHUSETTS GENERAL HOSPITAL · 2022 · $25,000

## Abstract

Project summary/ abstract:
The proposed conference project will be centered on the “Planning for Parkinson’s
Prevention: A trial design forum”, held October 2nd to 3rd, 2022. The overall long-term
objectives of this R13 program are to foster the education, training, and future research
of investigators in the emerging translational and clinical neuroscience theme of
preventative therapeutics for Parkinson’s disease (PD); and to further early initiatives
and trial efforts in PD prevention. These project objectives will be achieved through
three specific aims (SAs). SA #1 is to provide an update on current research in
prevention trial development with a focus on the critical trial design elements (via
symposium sessions), and to share and compare emerging clinical trial protocols and
initiatives (via presentations and discussion in an interactive session). The symposium
portion of the forum will cover i) whom to enroll (genetically and prodromally at-risk
populations), ii) what interventions to test, and iii) how to measure prevention of PD or
its progression prior to diagnosis (e.g., with biomarker or clinical assessments). SA #2 is
to increase research community engagement by enlisting at-risk advocates, providing a
hybrid conference format, and publicizing our forum widely. SA #3 is to provide
additional training in prevention therapeutics and facilitate networking opportunities for
early career investigators through creation of an educational curriculum.

## Key facts

- **NIH application ID:** 10538851
- **Project number:** 1R13NS129235-01
- **Recipient organization:** MASSACHUSETTS GENERAL HOSPITAL
- **Principal Investigator:** Grace Crotty
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $25,000
- **Award type:** 1
- **Project period:** 2022-08-01 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10538851

## Citation

> US National Institutes of Health, RePORTER application 10538851, Planning for Prevention of Parkinson's disease: A Trial Design Forum (1R13NS129235-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10538851. Licensed CC0.

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