# Training in Neurotherapeutics for Academic Scientists

> **NIH NIH R25** · UNIVERSITY OF CALIFORNIA AT DAVIS · 2022 · $270,000

## Abstract

Project Summary/Abstract
 This project will develop and implement a training program in neurotherapeutics discovery and
development for faculty members and advanced postdoctoral fellows, centered around a 4-day short course
that will provide the trainees with the various knowledge elements required to discover and advance a
neurotherapeutic agent – either small molecule or biological – to IND. The course is offered in conjunction with
the American Society for Experimental Neurotherapeutics (ASENT). The training, which is designed to be
applicable to diverse diseases of the nervous system, will equip students with a broad understanding of the
various component steps in the neurotherapeutics drug discovery and development process. Students will
learn how to identify a good drug discovery target; how to construct an assay; the elements of medicinal
chemistry; how to conduct animal efficacy testing; the principles of ADME studies, safety testing, and
formulation; special considerations for development of biological products, including monoclonal antibodies,
oligonucleotides and viral vector gene therapies; the steps required to prepare an IND document and the
principles for interacting with the FDA; the principles of intellectual property as they relate to
neurotherapeutics discovery and development; and how to seek funding for academic drug discovery
research. They will also receive training in responsible conduct of research. Students will be equipped with
the skills to develop and coordinate an entire drug discovery and development effort, and to work
collaboratively with experts in each of the component areas. The training will combine didactic lectures with
active engagement activities in which the students will be challenged to utilize the lecture material to work
through their own drug discovery project plan with the guidance of the area experts. The 4-day short course
will be offered annually, a total of five times. After attending the short course, trainees will participate in
ongoing activities that provide continuing professional development through engagement with ASENT.

## Key facts

- **NIH application ID:** 10539175
- **Project number:** 1R25NS129110-01
- **Recipient organization:** UNIVERSITY OF CALIFORNIA AT DAVIS
- **Principal Investigator:** MICHAEL A. ROGAWSKI
- **Activity code:** R25 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $270,000
- **Award type:** 1
- **Project period:** 2022-08-01 → 2027-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10539175

## Citation

> US National Institutes of Health, RePORTER application 10539175, Training in Neurotherapeutics for Academic Scientists (1R25NS129110-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10539175. Licensed CC0.

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