# Data Coordinating Center for the Pediatric Heart Network - MUSIC

> **NIH NIH U24** · NEW ENGLAND RESEARCH INSTITUTES, INC. · 2022 · $2,653,648

## Abstract

PROJECT SUMMARY/ABSTRACT
MUSIC is an observational cohort study that utilizes routinely collected clinical and cardiac (electrocardiogram
[EKG], echocardiogram, cardiac MRI [CMR], exercise testing) data to assess the association between
multisystem inflammatory syndrome in children associated with COVID-19 (MIS-C) and cardiac outcomes within
the first year after hospital discharge. The objective of the study is to determine the spectrum and time course of
coronary artery involvement, left ventricular (LV) systolic function, and arrhythmias or conduction system
disturbances within the first year from illness onset, and to define associated clinical and laboratory factors.
Approximately 1200 subjects will be enrolled and followed for up to 5 years after initial onset. The Specific Aim
of the DCC is to manage the MUSIC study development, launch, data collection and dissemination of results.

## Key facts

- **NIH application ID:** 10541019
- **Project number:** 3U24HL135691-05S1
- **Recipient organization:** NEW ENGLAND RESEARCH INSTITUTES, INC.
- **Principal Investigator:** Julie Elaine Miller
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $2,653,648
- **Award type:** 3
- **Project period:** 2017-07-01 → 2024-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10541019

## Citation

> US National Institutes of Health, RePORTER application 10541019, Data Coordinating Center for the Pediatric Heart Network - MUSIC (3U24HL135691-05S1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10541019. Licensed CC0.

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