BIOINFORMATICS AND DATA MANAGEMENT CORE (BDM) SUMMARY/ABSTRACT The Bioinformatics and Data Management Core (BDM) will provide data management, bioinformatic processing, and biostatistical analysis of the data created by the Projects as well as the IEC Core of this program. To accomplish these goals, the Core will provide: 1) database infrastructure, 2) database monitoring and management, 3) provide data queries for the Projects and other Cores as needed, 4) bioinformatics processing of raw high-throughput data, 5) biostatistical analysis support, 6) interaction with ImmPort (and other public data repositories), and 7) ongoing education and career enrichment for staff and study investigators. This Core will work closely with each Project and the IEC Core to ensure that raw data generated by each Project will be stored, processed, analyzed, and uploaded in a timely manner for the CPM Core to use for modeling purposes.