Summary The UMASH Center continues to develop productive multidisciplinary collaborations. Our work implements a One Health approach. Evidence of this is through our communications, collaborations, and cooperation of the varying human, animal, and environmental systems that are integral to health and safety. Our innovative research projects build on past success and address important and timely health and safety problems relevant to the agricultural workforce in the Upper Midwest, the country, and the world. The outreach and engagement activities are active, relevant, and forward-looking, with widely accessed and available resources. Our Emerging issues program addresses timely topics relevant to today's issues encompassing input from our human, animal, and environmental experts and stakeholders. We recognize the ever-changing agricultural landscape and our need to be nimble to address those needs. Our robust evaluation program and personnel will ensure our work will be impactful. The UMASH team looks forward to continuing to address issues related to the health and well-being of agricultural workers and their families.