# Southern California Clinical and Translational Science Institute

> **NIH NIH UL1** · UNIVERSITY OF SOUTHERN CALIFORNIA · 2022 · $9,009,695

## Abstract

Contact PD/PI: Buchanan, Thomas A
OVERALL COMPONENT
Project Summary/Abstract
The Southern California Clinical and Translational Science Institute (SC CTSI) is submitting this revision for a
third cycle of Clinical and Translational Science Award (CTSA) funding at a time of dramatic growth and
opportunity at our hub. The SC CTSI encompasses the University of Southern California (USC) and Children's
Hospital of Los Angeles (CHLA), in close partnership with the Los Angeles County Department of Health
Services. Our vision is to be a leader in clinical and translational research to benefit diverse communities and
special populations. Our approach builds on past success, acknowledging the changing landscape of clinical
and translational research (CTR), the priorities of the CTSA program, and the evolving needs of our
researchers, trainees, patients and communities. Our scope leverages strengths in clinical, health system, and
community research, education and training, within two overarching themes: diversity and impact. Diversity is
reflected in the communities, health systems, and scientific disciplines we engage to improve health care and
outcomes. Impact encompasses academic productivity as well as benefit to our workforce, health systems,
patients, and communities. To pursue our vision in the context of our scope and themes, we propose six
specific aims: (1) Workforce Development: Train a highly skilled workforce with the knowledge, skills, and
attitudes to conduct rigorous and reproducible research focused on the evolving health needs of diverse
communities. (2) Collaboration and Engagement: Create a culture in which team-based research, engaging all
stakeholders and following sound principles of team science, is the standard approach to addressing complex
challenges in health and research. (3) Integration: Engage our diverse communities to establish clinical
research priorities; identify barriers to research; and develop, demonstrate and disseminate innovative
approaches to assure fully partnered clinical research across communities and the lifespan. (4) Methods and
Process: Apply principles of quality and process improvement to clinical and translational research to develop
and share novel approaches to enhance efficiency, quality and impact. (5) Informatics: Provide an agile
information ecosystem that encompasses research, clinical care, communities and their environment, providing
a holistic view of health and disease and serving as the engine for discovery, innovation and insight. (6) CTSA
Hub: Participate in CTSA network activities, conduct multi-site studies, adopt successful models from peers,
and develop, demonstrate and disseminate innovative approaches. Achieving these aims will advance the
discipline of CTR directed at improving health in diverse and underserved communities.
Glossary
ACT – CTSA Program Accrual to Clinical Trials Network IRB – Institutional Review Board
BERD – Biostatistics, Epidemiology, Research Design core group ISI...

## Key facts

- **NIH application ID:** 10559463
- **Project number:** 2UL1TR001855-06A1
- **Recipient organization:** UNIVERSITY OF SOUTHERN CALIFORNIA
- **Principal Investigator:** Thomas A Buchanan
- **Activity code:** UL1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $9,009,695
- **Award type:** 2
- **Project period:** 2016-07-01 → 2027-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10559463

## Citation

> US National Institutes of Health, RePORTER application 10559463, Southern California Clinical and Translational Science Institute (2UL1TR001855-06A1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10559463. Licensed CC0.

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