# Bioinformatics Core

> **NIH NIH P30** · UNIVERSITY OF HAWAII AT MANOA · 2022 · $193,526

## Abstract

Project Summary for the Bioinformatics Core 
Explosive growth in powerful bioinformatics tools and continued refinements in well-annotated databases have 
accelerated the acquisition of new knowledge about the myriad genetic and epigenetic determinants of 
infectious diseases and other diseases that cause untold human suffering. In this regard, big-data science 
holds the promise for personalized, predictive, preventive and participatory medicine to improve human health 
and prevent disease. Thus, the importance of sustaining the Bioinformatics Core cannot be overstated. During 
COBRE Phase II, the Bioinformatics Core placed a major emphasis on providing customized support and 
collaborative services, on developing new and improved bioinformatics tools, and on conducting intensive 
educational courses and hands-on training workshops. 
The Phase III COBRE objective of facilitating the transition of the Bioinformatics Core into a sustainable state- 
of-the-art core facility capable of supporting high-caliber research on new, emerging and re-emerging 
infectious diseases, as well as other fields of scientific inquiry, will be achieved by (1) enhancing and 
streamlining core operations; (2) growing and diversifying the user base, capability, capacity and reach; and 
(3) strengthening the core infrastructure. For Aim 1, needs assessments and user satisfaction surveys will be 
conducted to ensure efficiency and effectiveness of core operations at the core/user interface and user 
services. For Aim 2, outreach and marketing activities will be expanded to other local academic institutions, 
biotech companies and hospitals beyond the UH System, and strong partnerships will be formed with similar 
cores located in other COBRE, INBRE and IDeA-CTR programs to further grow and diversify the core user 
base and to acquire new tools and techniques. And for Aim 3, institutionalization and phased-in business plans 
will be developed during the Phase III COBRE to draw on intramural and extramural sources for sustainability. 
It is envisioned that the Bioinformatics Core will achieve each of the above-stated specific aims. A strong 
commitment by the President of the UH System to fully support the Bioinformatics Core infrastructure, with 
professional positions and support staff, within the next five years is part of a larger strategic plan to 
institutionalize bioinformatics as one of the four principal pillars in the Division of Cyberinfrastructure. Thus, 
there is every reason to be optimistic that the Bioinformatics Core will be transformed into a system-wide 
bioinformatics resource to confront the challenges of big-data science.

## Key facts

- **NIH application ID:** 10576204
- **Project number:** 3P30GM114737-05S2
- **Recipient organization:** UNIVERSITY OF HAWAII AT MANOA
- **Principal Investigator:** Youping Deng
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $193,526
- **Award type:** 3
- **Project period:** 2022-03-14 → 2023-07-13

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10576204

## Citation

> US National Institutes of Health, RePORTER application 10576204, Bioinformatics Core (3P30GM114737-05S2). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10576204. Licensed CC0.

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