# A Synchrotron Radiation Structural Biology Resource

> **NIH NIH P30** · STANFORD UNIVERSITY · 2022 · $265,880

## Abstract

Summary/Abstract - P30GM133894
Synchrotron radiation (SR) is an extremely bright and tunable x-ray source that enables forefront
research in structural molecular biology (SMB). The goal of “A Synchrotron Structural Biology
Resource" at the Stanford Synchrotron Radiation Lightsource (SSRL), hereafter referred to as
simply “Resource”, is to provide users access to integrated, mature SMB capabilities utilizing
state-of-the-art synchrotron beam line facilities for macromolecular crystallography, x-ray
absorption/emission/imaging spectroscopy and small angle x-ray scattering/diffraction. These
three areas comprise the Resource’s three Technical Operations Cores. Special emphasis is to
create streamlined user access, provide dedicated user support and services, to train users, and
to perform outreach on the scientific benefits of the capabilities of these specialized, yet mature
facilities to the biomedical research community. Multiple innovative access mechanisms are
being provided, that include both single- and multiple-technique approaches to access the Cores,
based on a transparent and robust external peer-review process. A multifaceted training and
outreach program includes individual training, workshops, summer schools, on-the-road, and
support clinic segments by experienced scientific and technical staff. A Resource web portal
provides streamlined scientific, technical, training, outreach and administrative material and other
relevant information. A principal aim is to optimize and maintain, for reliable and forefront
performance, experimental facilities and instrumentation, detectors, software and computing and
network capabilities on the Resource’s 8+ beam lines at SSRL, capitalizing on the high SR x-ray
performance of SSRL’s 3rd generation storage ring SPEAR3, and at the MFX station at LCLS. A
multi-facility proposal mechanism facilitates access to complementary Cryo-EM and LCLS
stations on-site at SLAC. With a specialized focus on user training, support and service, the
Resource enables the scientific success for challenging and routine projects in the biomedical
sciences.

## Key facts

- **NIH application ID:** 10579751
- **Project number:** 3P30GM133894-03S1
- **Recipient organization:** STANFORD UNIVERSITY
- **Principal Investigator:** KEITH O HODGSON
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $265,880
- **Award type:** 3
- **Project period:** 2020-06-01 → 2025-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10579751

## Citation

> US National Institutes of Health, RePORTER application 10579751, A Synchrotron Radiation Structural Biology Resource (3P30GM133894-03S1). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10579751. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*