# Equipment Supplement to 1R01GM141391-01A1 (Easily Used Kits to Evolve Reagents that Covalently Tag and Inactivate Proteins)

> **NIH NIH R01** · FOUNDATION FOR APPLIED MOLECULAR EVOLUTN · 2022 · $134,966

## Abstract

Equipment Supplement for 1R01GM141391-01A1
(Easily Used Kits to Evolve Reagents that Covalently Tag and Inactivate Proteins)
 Foundation for Applied Molecular Evolution
 Steven Benner
Abstract
The Foundation for Applied Molecular Evolution (FfAME) holds a current NIGMS R01 research
award (R01GM141391, Easily Used Kits to Evolve Reagents that Covalently Tag and Inactivate
Proteins). Under this award, FfAME is requesting supplemental equipment funds that will be
used to replace a 16-year-old BioRad PMI phosphorimager, an instrument that serves as the
workhorse for the R01 project.
The main goal of the funded R01 grant is to utilize FfAME’s artificially expanded genetic
alphabet (AEGIS) to develop a platform to create receptors, ligands, and catalysts on demand.
These molecules can be used to covalently modify, tag, and destroy proteins that are chosen by
researchers and clinicians to target and solve many scientific, diagnostics, and disease
management problems.
This administrative supplement, if granted, will facilitate the purchase of an Amersham
Typhoon Biomolecular Imager, which will replace the BioRad PMI and will serve a critical role
in the success of the funded R01 project.

## Key facts

- **NIH application ID:** 10580301
- **Project number:** 3R01GM141391-02S1
- **Recipient organization:** FOUNDATION FOR APPLIED MOLECULAR EVOLUTN
- **Principal Investigator:** STEVEN A BENNER
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $134,966
- **Award type:** 3
- **Project period:** 2021-09-01 → 2025-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10580301

## Citation

> US National Institutes of Health, RePORTER application 10580301, Equipment Supplement to 1R01GM141391-01A1 (Easily Used Kits to Evolve Reagents that Covalently Tag and Inactivate Proteins) (3R01GM141391-02S1). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10580301. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*