# Strategies and Methods for Complex Molecule Synthesis: Acquisition of a 400 MHz Nuclear Magnetic Resonance Spectrometer Console

> **NIH NIH R35** · UNIVERSITY OF CALIFORNIA BERKELEY · 2022 · $217,626

## Abstract

Project Summary/Abstract
The goal of this program is to develop new strategies and methods for the synthesis of
biologically active secondary metabolites (natural products). A significant portion of our efforts
will be dedicated to identifying efficient preparations of these complex molecules. These
compounds and their unique derivatives will serve as novel small molecules to combat a range
of indications associated with cancer as well as inflammation and pain. Our synthetic studies
will lead to new applications of C–C bond activation methodology in organic synthesis as well
as a Network Analysis approach to the preparation of topologically complex molecules. Our
work will also highlight new directions for the use of carvone as a sustainable starting material
for synthesis. Finally, working with collaborators, we will gain unique entry into the use of
natural products and their derivatives to perturb biological function and ultimately provide
promising starting points for new therapeutics.

## Key facts

- **NIH application ID:** 10581086
- **Project number:** 3R35GM130345-04S1
- **Recipient organization:** UNIVERSITY OF CALIFORNIA BERKELEY
- **Principal Investigator:** Richmond Sarpong
- **Activity code:** R35 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $217,626
- **Award type:** 3
- **Project period:** 2019-01-01 → 2023-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10581086

## Citation

> US National Institutes of Health, RePORTER application 10581086, Strategies and Methods for Complex Molecule Synthesis: Acquisition of a 400 MHz Nuclear Magnetic Resonance Spectrometer Console (3R35GM130345-04S1). Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/grant/nih/10581086. Licensed CC0.

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