# Excitable Networks in Directed Cell Migration

> **NIH NIH R35** · JOHNS HOPKINS UNIVERSITY · 2022 · $200,000

## Abstract

Directed cell migration is critical in development and in numerous physiological processes in the
adult such as wound healing and immune response. It also plays a critical role in pathological
events like cancer metastasis. Our lab has been studying cell migration for over 40 years. As a
supplement to our MIRA grant, we are requesting funds to purchase a Total Internal Reflection
Fluorescence Microscope with superresolution capability. As described in the research plan this
instrument is essential for imaging the many biosensors we use in our studies. The instrument
we have available currently is 15 years old and lacks the modern technology that would greatly
facilitate our studies. We neglected to consider the need for this instrument in the original
application for renewal of the MIRA.
The instrument is approximately $254337. I am requesting $200000 as a supplement to my
MIRA grant. The Department of Cell Biology will provide institution support of $54337 (see
letter from Dr. Ewald).

## Key facts

- **NIH application ID:** 10581845
- **Project number:** 3R35GM118177-07S1
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** Peter N Devreotes
- **Activity code:** R35 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $200,000
- **Award type:** 3
- **Project period:** 2016-05-01 → 2026-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10581845

## Citation

> US National Institutes of Health, RePORTER application 10581845, Excitable Networks in Directed Cell Migration (3R35GM118177-07S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10581845. Licensed CC0.

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