# Nutrient-dependent regulation of neural stem cell proliferation and neural circuit formation

> **NIH NIH R35** · UNIVERSITY OF VIRGINIA · 2022 · $16,402

## Abstract

PROJECT SUMMARY
We are seeking to acquire supplemental funds to support the purchase of an incubator that will
be used in our research that is currently funded by a R35 award. Our current R35 is aimed at
uncovering genetic and molecular mechanisms that regulate neural stem cell proliferation
decisions in response to dietary nutrient availability and the nutrient-regulated neuronal circuitry
that controls these decisions. We use Drosophila melanogaster as a model system. In order to
use Drosophila in a laboratory setting, a temperature, humidity, and light/dark cycle controlled
incubator is needed to house the animals and for developmental staging experiments.

## Key facts

- **NIH application ID:** 10581868
- **Project number:** 3R35GM141886-02S1
- **Recipient organization:** UNIVERSITY OF VIRGINIA
- **Principal Investigator:** Sarah Elizabeth Siegrist
- **Activity code:** R35 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $16,402
- **Award type:** 3
- **Project period:** 2021-07-01 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10581868

## Citation

> US National Institutes of Health, RePORTER application 10581868, Nutrient-dependent regulation of neural stem cell proliferation and neural circuit formation (3R35GM141886-02S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10581868. Licensed CC0.

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