# The FYI on MRI: A Multilevel Decision Support Intervention for Screening Breast MRI

> **NIH NIH K08** · GEORGETOWN UNIVERSITY · 2023 · $194,297

## Abstract

PROJECT SUMMARY
The proposed K08 career development award will provide Dr. Conley with the training and mentorship necessary
to become an independent clinical scientist focused on leveraging multilevel approaches to support informed
decision making about risk-based cancer screening in diverse populations. She has identified decision-making
about screening breast MRI among high-risk Black and Latina women as a critical issue to address in order to
achieve this goal. This proposal describes a 5-year comprehensive program of training and mentored research
for an academic career at the intersection of medical decision making and risk-based cancer screening. This
K08 will provide key training in community engaged research, medical decision making, multilevel interventions,
and cancer risk prediction models. The intensive research experience provided by the K08 aims will provide the
opportunity to implement and practice the skills gained through the training goals. The primary objective of the
proposed research is to develop and test a multilevel intervention to support informed decision making about
screening breast MRI among high-risk Black and Latina women. Women at high risk for breast cancer (i.e., ≥20%
lifetime risk) can decide to supplement mammography screening with MRI or continue with mammography alone.
Some women will benefit from screening with breast MRI, though some will experience harms due to the higher
rate of biopsies, false-positive results, and higher costs. Thus, informed decision making about screening breast
MRI is critical for high-risk women. An informed decision is defined as a decision that is made with sufficient
knowledge, and is in line with the person’s preferences. To make informed decisions about screening breast
MRI, high-risk women must: (1) be identified as high risk; (2) be made aware that breast MRI is an option; (3)
understand MRI’s benefits and drawbacks; and (4) make a decision aligned with their preferences. However,
lack of awareness and access may prevent high-risk Black and Latina women from making an informed decision
about breast MRI. The study’s specific aims are: (1) develop and deliver a universal breast cancer risk assess-
ment protocol in a community setting; (2) develop a culturally-relevant decision aid with input from diverse stake-
holders; and (3) assess the effect of the multilevel decision support intervention (i.e., risk assessment + decision
aid) on informed decisions about breast MRI. Dr. Conley’s mentorship team – including world-renowned behav-
ioral scientists, clinical trialists, breast oncologists, epidemiologists, and biostatisticians – will provide guidance
to support her research aims and complement her didactic training. These factors, in addition to the supportive
research environment at Georgetown Lombardi Comprehensive Cancer Center, will enable her to achieve the
proposed project aims. The proposed study will provide pilot data for a future R01 application to test the effec-
tiv...

## Key facts

- **NIH application ID:** 10591106
- **Project number:** 1K08CA270402-01A1
- **Recipient organization:** GEORGETOWN UNIVERSITY
- **Principal Investigator:** Claire C Conley
- **Activity code:** K08 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $194,297
- **Award type:** 1
- **Project period:** 2023-04-05 → 2028-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10591106

## Citation

> US National Institutes of Health, RePORTER application 10591106, The FYI on MRI: A Multilevel Decision Support Intervention for Screening Breast MRI (1K08CA270402-01A1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10591106. Licensed CC0.

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