PROJECT SUMMARY The Administrative Core will be responsible for overseeing the establishment of the Integrative Center for Precision Nutrition and Human Health COBRE at the University of Hawaii at Manoa (UHM) and ensuring its overall success, growth and sustainability. Consisting of the COBRE Director, Program Coordinator, Executive Committee and Mentoring Teams, the Administrative (Admin) Core will provide comprehensive logistical and administrative support for the individual Research Projects and Research Project Leaders (RPL), the Core facilities, and in conjunction with the Community Engagement and Outreach Core (CEO), the Community Pilot Project Program and Outreach. The Admin Core will be responsible for the ongoing evaluation, assessment and corrective actions within the COBRE, planning and coordinating the External Advisory Committee (EAC) meetings and communicating with the External and Internal Advisory Committees (IAC), preparing Annual Progress Reports, and coordinating all interactions with NIH program officials related to the COBRE. Working with the Fiscal and Human Resources Departments at JABSOM, the Admin Core will oversee management of the budgets and annual fiscal reports, equipment maintenance and inventories, and employee records. The overall goals of the Admin Core are to oversee the successful development and implementation of a sustainable Integrative Center for Precision Nutrition and Human Health at UH, through the processes and interactions necessary to carry out the duties and responsibilities to accomplish the goals of the Core. The goals of the Admin Core will be achieved through the following three Aims: Aim 1: To develop and implement strategies for efficient, effective management of administrative, fiscal, and scientific aspects of the Center; Aim 2: To develop mentoring strategies that foster scientific and professional development of Research Project Leaders to ensure their attainment of independent investigator status and R01 or equivalent funding; Aim 3: To establish and implement a COBRE Pilot Project Program to support research proposals. The Admin Core will have achieved its goals if it is successful in establishing the foundation and enhancing the research infrastructure and environment that fosters the development of a cadre of extramurally-funded future leaders in Precision Nutrition research.