# Cancer Pain Management: A Technology-Based Intervention for Asian American Breast Cancer Survivors

> **NIH NIH R61** · EMORY UNIVERSITY · 2022 · $744,214

## Abstract

Due to cultural stigma attached to breast cancer, cultural stoicism toward pain and symptoms, and language
barriers, Asian American breast cancer survivors tend to suffer unnecessarily from pain that could be easily
managed using existing pharmacologic or non-pharmacologic strategies. Especially, Asian American breast
cancer survivors with depressive symptoms (ABD) are more likely to have inadequate pain management due
to their depression, and pain could further deteriorate depression. Furthermore, the recent opioid crisis has
exacerbated their fear of addiction and reluctance to seek help for pain management. The COVID19 pandemic has also placed an additional dimension of stress to this specific population. However, survivorship programs at cancer centers lack the staff and time to adequately address these unique needs of this population. A technology-based approach using computers and mobile devices promises to meet this necessity with high
flexibility, accessibility, and anonymity. Based on Preliminary Studies (PSs), the research team developed and
pilot-tested an evidence-based Web App-based information and coaching/support program for cancer pain
management (CAPA) that was culturally tailored to Asian American breast cancer survivors using multiple
unique features. However, CAPA rarely considered depressive symptoms accompanying pain in its design or
components, and PSs indicated the necessity of further individualization of the intervention components of
CAPA due to diversities in the needs of ABD. The purpose of the proposed 2-phase study is to further
develop CAPA with additional components for ABD and the individual optimization functionality (CAI) and to
test the efficacy of CAI in improving cancer pain experience of ABD. The specific aims are to: a) develop
and evaluate CAI through an expert review and a usability test (R61 phase); b) determine whether the
intervention group (that uses CAI and usual care) will show significantly greater improvements than the active
control group (that uses CAPA and usual care) in primary outcomes (cancer pain management and cancer
pain experience including depressive symptoms) from baseline to post 1-month and post 3-months; c) identify
theory-based variables (attitudes, self-efficacy, perceived barriers, and social influences) that mediate the
intervention effects of CAI on the primary outcomes; and d) determine whether the effects of CAI on the
primary outcomes are moderated by selected background, disease, genetic, and situational factors. This study
is guided by the Bandura’s Theory and the stress and coping framework by Lazarus and Folkman. The R61
phase includes: (a) the intervention development process, (b) a usability test among 15 ABD, 15 family
members, and 15 community gatekeepers; and (c) an expert review among 10 experts in oncology. The R33
phase adopts a randomized repeated measures control group design among 300 ABD. Long-term goals are:
(a) to extend and test CAI in various healthcare ...

## Key facts

- **NIH application ID:** 10595357
- **Project number:** 1R61CA280979-01
- **Recipient organization:** EMORY UNIVERSITY
- **Principal Investigator:** Wonshik Chee
- **Activity code:** R61 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $744,214
- **Award type:** 1
- **Project period:** 2022-09-20 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10595357

## Citation

> US National Institutes of Health, RePORTER application 10595357, Cancer Pain Management: A Technology-Based Intervention for Asian American Breast Cancer Survivors (1R61CA280979-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10595357. Licensed CC0.

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