# The EMBER Trial for Weight Management Engagement

> **NIH VA I01** · VETERANS ADMIN PALO ALTO HEALTH CARE SYS · 2024 · —

## Abstract

Background: Almost 40% of Veterans using the Veterans Health Administration (VA) have obesity, putting
millions at risk for costly and debilitating conditions, including diabetes, cancer, and severe COVID-19. VA
weight management programs effectively reduce weight, morbidity, and mortality. For example, MOVE!, VA’s
flagship program for weight management is associated with reductions in cardiovascular disease and diabetes.
However, while 94% of eligible Veterans are offered weight management programs, less than 8% use them.
 Motivational interviewing improves treatment engagement, but clinicians have limited time to apply it.
Therefore, we developed EMBER, a self-directed tool with the goal of Enhancing Motivation for Better
Engagement and Reach for weight management. It is available in paper and digital formats. EMBER is not a
weight management program, instead it engages Veterans in existing programs by informing and guiding
choices about weight management. EMBER is the product of an HSR&D Career Development Award (15-257).
Significance: If EMBER increases engagement in effective weight management programs, it has the potential
to help Veterans lose weight, thereby improving health and quality of life for thousands of patients. As a result,
we address many HSR&D priorities, e.g.,
access to care, virtual care, healthy equity, & primary care.
Innovation & Impact: EMBER is the first self-directed, motivational interviewing-based intervention designed
to increase Veteran engagement in weight management programs. As opposed to a “one-off” study in a
specific population, the proposed work takes a novel, low-touch population health approach that could be
translated to other programs (e.g., behavioral pain management). EMBER also includes vignettes relevant to
populations at high risk for obesity (e.g., women, people of color).
Further, t
he Hybrid Type 1 design will ensure
results can be scaled and sustained while also advancing implementation science. As such, the proposed work
will: 1) advance the science of engagement in behavioral health programs and 2) facilitate future research on
the implementation of EMBER and similar interventions.
Specific Aims:
1. Assess whether Veterans randomized to EMBER are more likely to have any weight management
engagement at 2-month follow-up (per administrative data supplemented with self-report) compared to
 those randomized to the control arm (information sheet listing available programs). (Primary Outcome)
2. Assess whether Veterans randomized to EMBER have greater weight management program retention,
weight management behaviors (e.g., physical activity), weight loss, and quality of life gains at 6-month
 follow-up compared to those randomized to the control arm. (Secondary Outcomes)
3. Assess factors likely to affect EMBER’s implementation. Preliminary implementation outcomes will be
assessed via RE-AIM4 (Reach, Effectiveness, Implementation) and the Proctor et al.5 implementation
outcomes framework (Acceptabili...

## Key facts

- **NIH application ID:** 10595507
- **Project number:** 5I01HX003082-02
- **Recipient organization:** VETERANS ADMIN PALO ALTO HEALTH CARE SYS
- **Principal Investigator:** Jessica Yelena Breland
- **Activity code:** I01 (R01, R21, SBIR, etc.)
- **Funding institute:** VA
- **Fiscal year:** 2024
- **Award amount:** —
- **Award type:** 5
- **Project period:** 2022-02-01 → 2025-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10595507

## Citation

> US National Institutes of Health, RePORTER application 10595507, The EMBER Trial for Weight Management Engagement (5I01HX003082-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10595507. Licensed CC0.

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