# Specific Pathogen Free Baboon Research Resource (SPFBRR) - Bridge Funding Administrative Supplement

> **NIH NIH P40** · UNIVERSITY OF TX MD ANDERSON CAN CTR · 2022 · $900,000

## Abstract

PROJECT SUMMARY
This application is a request for bridge funding for the “Specific Pathogen Free Baboon Research
Resource” (SPFBRR) P40 OD024628. The SPFBRR was founded with NIH support at the University of
Oklahoma Health Sciences Center (OUHSC) in 2002 and was relocated to the Keeling Center in 2017. The
SPFBRR has received continuous NIH support since it was founded. The SPFBRR is the only national
research resource of adventitious virus free olive baboons (Papio anubis) that are available to NIH grantees;
intramural research programs of federal agencies, including the FDA, NSF and NIH; and other sponsors of
biomedical research (private foundations, pharmaceutical companies, and contract research organizations).
Absolutely unique in the entire world, the baboons in the SPFBRR have an extensive bioexclusion list of 18
pathogens normally found in other wild and captive nonhuman primate colonies. The SPFBRR has
integrated multiple disciplines into a program designed to meet the needs of investigators who utilize its
resources. During the proposed period of support, the SPFBRR will continue to improve the resources it
provides to users and will continue to add new information about the biology and research value of virus free
baboons to its website. Baboons continue to be important animal model for genetically engineered pig
xenotransplantation, are the only NHP model of respiratory syncytial virus and whooping cough, and they
remain a very important model of bacterial sepsis. Additionally, baboons are excellent models of human
COVID associated pneumonia, and they were instrumental in the development of approved vaccines for
SARS CoV-2. Over the next year the SPFBRR will focus on maintaining the SPF18 baboon breeding colony
to meet current and future biomedical research needs. The overall goal of the SPFBRR is to provide a
national research resource of virus free olive baboons; provide baboon derived biological materials;
provide education and training opportunities to scientist, colony managers, and animal caregivers
who want to work with baboons; and to provide investigators with facilities and expertise to conduct
studies using virus free baboons.

## Key facts

- **NIH application ID:** 10596840
- **Project number:** 3P40OD024628-05S4
- **Recipient organization:** UNIVERSITY OF TX MD ANDERSON CAN CTR
- **Principal Investigator:** Joe H. Simmons
- **Activity code:** P40 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $900,000
- **Award type:** 3
- **Project period:** 2022-06-01 → 2023-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10596840

## Citation

> US National Institutes of Health, RePORTER application 10596840, Specific Pathogen Free Baboon Research Resource (SPFBRR) - Bridge Funding Administrative Supplement (3P40OD024628-05S4). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10596840. Licensed CC0.

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