Project Summary/Abstract - Overall The Michigan Center for Diabetes Translational Research (MCDTR) supports 110 current members, regional, national, and international collaborators, and aims to engage and support new members in multiple disciplines to conduct T2-T4 diabetes research with a specific emphasis on novel approaches to measure and improve health equity. Over past years, the MCDTR has expanded its research base focused on community and health system interventions that span T2-T4 translation. There is a great need now to support new research evaluating novel approaches to improve health equity in diabetes prevention and management and to incorporate rigorous measurement of and innovative strategies to improve health equity within all our members' research. We aim to promote research that supports the development, implementation, evaluation, and dissemination of effective interventions, programs, and policies that improve health outcomes and equity. The MCDTR will:1) Raise awareness of and interest in T2-T4 translational research in diabetes and create an environment that supports important and innovative research; 2) Foster and help sustain multidisciplinary, novel, and cross-sectoral collaborations, including with multiple health and social service organizations where appropriate to advance emerging scientific areas of translational and health equity research; 3) Provide core services to support members’ research programs using best practices in translational and health equity research; 4) Through enrichment, pilot and feasibility grant, and other programs, attract, develop, and support early and other researchers to conduct research that improves diabetes prevention, treatment, population health, and health equity. The Center supports four cores. The Administration Core maintains the Research Base and is responsible for the MCDTR's direction, functioning, finances, and web site. It administers the Pilot and Feasibility Study Grants Program, the Enrichment Program, and the Cross-Sectoral Collaborations initiative that fosters and sustains partnerships between MCDTR investigators and multiple sectoral partners that span local and state health departments, federally qualified health centers, and community organizations. The Evaluation Methods and Intervention Strategies Core focuses on cutting-edge design and analysis methods and technology-based approaches to intervention delivery, cross-sectoral communication, and outreach to improve access of and ongoing support to populations facing health disparities. The Addressing Social and Behavioral Determinants of Health Core provides expertise on state-of-the art approaches to identify, measure, and meet unmet socio- economic needs and design interventions and policies that effectively address both social and behavioral determinants of improved diabetes and population health outcomes. The Leveraging Community, Family, and Peer Support Core helps investigators design and evaluate novel interve...