# Biostatistics and Bioinformatics Shared Resource

> **NIH NIH P30** · UNIVERSITY OF COLORADO DENVER · 2023 · $1

## Abstract

ABSTRACT 
Overview: The University of Colorado Cancer Center (UCCC) Biostatistics and Bioinformatics Shared Resource 
(BBSR) supports UCCC members and other Shared Resources (SRs) by providing biostatistical and 
bioinformatic expertise and services for laboratory-based research, experimental therapeutic studies, population 
sciences research, and clinical trials. Services: The BBSR provides biostatistical and bioinformatics support at 
all stages of projects. Pre-study assistance includes study design, sample-size calculations, and 
statistical/bioinformatic planning as needed for grant and clinical trial development. The BBSR also provides 
consultation and safety monitoring of clinical trials. Data analysis is provided in the form of statistical 
methodologies, interactive data analysis software, and assistance in preparing manuscripts and follow-up grant 
applications. The BBSR participates in the Protocol Review and Monitoring System (PRMS) and Data and Safety 
Monitoring Committees (DSMC). Expertise: The BBSR is comprised of 8 PhD-, 4 Master's-, and 2 Bachelor's- 
level researchers who collectively offer substantial expertise in clinical trial design and analysis, longitudinal data 
analyses, confounder adjustment, multi-omic data analysis, software development, predictive modeling, and 
cancer-focused bioinformatics. Management: The BBSR is comprised of two equal, collaborative, but distinct 
components – biostatistics and bioinformatics. Both are financially managed by the UCCC and overseen by the 
Associate Director of Basic Research, H Ford. Use of Services: Since 2016, the BBSR has worked with 236 
investigators. UCCC members representing all 4 programs account for ~85% of the total effort for the period and 
resulted in 136 publications, 28% of which have an IF>10; and 38 funded grants. Operating Budget: CCSG 
support represents 39% of the annual budget, with the remainder from direct grant support for BBSR staff (16%), 
chargebacks (17%) and institutional funds (28%). Innovation and Development: The BBSR has contributed to 
UCCC members' research through development of interactive analysis platforms that researchers use to explore 
their own large datasets. These platforms have been heavily utilized by UCCC members (7472 analysis hours 
in FY2020). BBSR is also developing data analysis tools to assist other SRs and their users. Consultation and 
Education: The BBSR contributes to UCCC members' research by conducting one-on-one training and hosting 
a monthly seminar series focused on bridging gaps between experimental wet lab research, new technologies 
(e.g. MIBI, single cell sequencing), and the biostatistical and bioinformatic analysis methods for associated data. 
Future Directions: The landscape in cancer research is continually changing with new technologies (e.g., 
multispectral, spatial imaging) and methodology (e.g., adaptive clinical trial design) being developed to advance 
our basic and clinical understanding of cancer. B...

## Key facts

- **NIH application ID:** 10599141
- **Project number:** 5P30CA046934-35
- **Recipient organization:** UNIVERSITY OF COLORADO DENVER
- **Principal Investigator:** RICHARD D SCHULICK
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $1
- **Award type:** 5
- **Project period:** 1997-04-04 → 2027-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10599141

## Citation

> US National Institutes of Health, RePORTER application 10599141, Biostatistics and Bioinformatics Shared Resource (5P30CA046934-35). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10599141. Licensed CC0.

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