# Pathology Shared Resource

> **NIH NIH P30** · UNIVERSITY OF COLORADO DENVER · 2023 · $1

## Abstract

ABSTRACT 
Overview: The Pathology Shared Resource (PSR) merges the Tissue Biobank and Histology SR and Molecular 
Pathology SRs into a single entity. The PSR, through four integrated sections, provides specialized expertise 
and an extensive array of services to support basic and translational research. Services and Expertise: The 
PSR leverages the clinical infrastructure of the Dept. of Pathology (DOP) to provide researchers access to a full 
spectrum of expertise in biobanking, pathology, histology, molecular pathology, and cytogenetics. Services 
include archival and real-time biospecimen collection, management, clinical trial support, and access to 
annotated biospecimens. Associated curated comprehensive clinical, pathologic, and molecular data is provided 
through the Pathology Data Warehouse and Health Data Compass in collaboration with the Biostatistics and 
Bioinformatics SR. Research Histology provides histology and immunohistochemistry services on animal and 
human tissue specimens. Molecular Pathology offers CLIA-level pre-analytical and molecular testing services; 
and the Cytogenetics section offers analysis for cancer genomic aberrations at chromosomal and whole genome 
levels. The PSR is equipped to support basic and translational research projects and support the logistics for 
institutional and multi-institutional clinical trials including investigator-initiated trials (IIT). Management: The PSR 
is managed by the Department of Pathology with oversight of CCSG resources performed by UCCC's Associate 
Director for Basic Research. Operating Budget: CCSG funding represents 13% of the annual $2.5M operating 
budget with the remaining from user fees (46%), institutional support (26%) and other grants (15%). 
Consultation and Education: The PSR provides education to research teams on proper biospecimen practices, 
clinical and research laboratory testing, and biomarker assay development using individual consultations and 
group seminars. Innovation: The PSR has established strategic partnerships with other SRs, including the 
Human Immune Monitoring, Mass Spectrometry, Genomics, Flow, and Cell Technologies SRs to provide 
specialized biospecimen analysis and access to high-throughput biomarker analysis platforms. Over the last 
funding cycle investments of $2.5M institutional funds have enabled centralization of biobanking and expansion 
of data capabilities, leading to improved availability of biospecimens with annotated clinicopathological data and 
shorter turn-around times for projects. Use of Services: During the last funding period >10k services and >20k 
specimens were provided to 290 investigators (48% UCCC members), supporting 350 clinical trials, 20 IITs, and 
basic research projects resulting in 117 cancer related publications. Future Directions: Annotation of 
biospecimen cohorts will be enhanced with pathological, clinical, and molecular data and made available in 
formats, such as TMAs, that enable high-throughput analy...

## Key facts

- **NIH application ID:** 10599173
- **Project number:** 5P30CA046934-35
- **Recipient organization:** UNIVERSITY OF COLORADO DENVER
- **Principal Investigator:** RICHARD D SCHULICK
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $1
- **Award type:** 5
- **Project period:** 1997-04-04 → 2027-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10599173

## Citation

> US National Institutes of Health, RePORTER application 10599173, Pathology Shared Resource (5P30CA046934-35). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10599173. Licensed CC0.

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