# Children's National Hospital Site Consortium  - Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Operations and Collaborations Center (UM2 Clinical Trial Optional)

> **NIH NIH UM2** · WESTAT, INC. · 2022 · $335,019

## Abstract

ABSTRACT Children's National Hospital (CNH) CRS
Despite the substantial progress in the HIV epidemic, adolescents, and young adults (AYA) aged 13-24 years
living with HIV have worse health outcomes compared to any other age groups in the United States (US).
Children's National Hospital (CNH), provides comprehensive HIV prevention and treatment services to the
majority of AYA from the District of Columbia (DC) eligible metropolitan area (EMA) including three national
HIV epidemic hotspots—Washington, DC, and two Maryland counties (Montgomery and Prince George's).
Within DC, which continues to have the highest rates of new HIV infection in the United States, AYA have a
high HIV prevalence of 0.3%, and high incidence of sexually transmitted infections, placing them at substantial
risk for acquiring HIV. Through universal HIV counselling and opt-out screening, CNH reaches out to
thousands of AYA in the DC EMA yearly with HIV prevention and testing services. Currently ~300 primarily
minority Black AYA are in care at CNH for pre-exposure prophylaxis and antiretroviral treatment. CNH has a
longstanding history of collaboration within local, regional, and national scientific networks, including prior
participation in the Adolescent Trials Network (ATN). CNH has served as a successful recruitment site to
multiple industry-sponsored investigational new drug clinical trials and received an uninterrupted line of DC
Department of Health funding for HIV prevention and testing for more than 10 years. CNH has well-established
partnerships with local and regional community-based organizations and a strong track-record of leadership in
AYA HIV research within the broader local community of academic and community-based investigators,
including its active role in DC Center for AIDS Research and DC Cohort Study. The overarching goal of the
proposed ATN CNH consortium site is to contribute to the Westat-led ATN Operation and Collaboration Center
(OCC) long-term scientific impact while expanding its role in delivering direct public health impacts on the local,
regional, and national HIV epidemic among AYA. To achieve this goal, CNH will: (a) actively participate in the
development and implementation of the Westat-led ATN OCC clinical trials identified by the ATN Executive
and Scientific Leadership Committees; (b) deliver innovative solutions to optimize recruitment, enrollment, and
retention of AYA at multiple sites in the DC EMA in ATN studies and ensure local laboratory capacity and
pharmacy support; (c) propose novel concepts, approaches, and methodologies in implementation and clinical
science, and development and optimization of biomedical prevention and treatment tools for AYA; and
(d) meaningfully contribute to the Westat-led ATN OCC leadership model through sustained CNH site and AYA
community engagement, expanding network collaborations through established regional collaborations among
clinical, academic, community-based AYA focused partners, local DOHs, and s...

## Key facts

- **NIH application ID:** 10599559
- **Project number:** 1UM2HD111076-01
- **Recipient organization:** WESTAT, INC.
- **Principal Investigator:** Natella Yurievna Rakhmanina
- **Activity code:** UM2 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $335,019
- **Award type:** 1
- **Project period:** 2022-09-22 → 2029-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10599559

## Citation

> US National Institutes of Health, RePORTER application 10599559, Children's National Hospital Site Consortium  - Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Operations and Collaborations Center (UM2 Clinical Trial Optional) (1UM2HD111076-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10599559. Licensed CC0.

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