# Upgrade of confocal microscopy at the Oregon National Primate Research Center

> **NIH NIH P51** · OREGON HEALTH & SCIENCE UNIVERSITY · 2022 · $499,999

## Abstract

PROJECT SUMMARY/ABSTRACT
The Integrated Pathology Core (IPC) at the Oregon National Primate Research Center (ONPRC), major
research center at Oregon Health & Science University (OHSU), requests funds for a Leica Stellaris 8 confocal
microscope. The Stellaris 8 instrument will replace an aging Leica SP5 confocal, which has been in place since
2008, and does not meet current user needs such as multiplexing, live-cell imaging, scanning of large tissue
areas such as the brain, and clarified thick sections. The new instrument's high resolution, sensitivity, and fast
scan rates will increase both the quality and productivity of research at ONPRC. This instrument represents a
significant technological advance, including a continuous-wavelength, tunable white-light laser, which provides
up to 8 wavelengths from 440 to 790 nm, flexible spectral detection, TauSense technology, Acouso Optic
Tunable Filter and Beam Splitter, and Power HyD detectors, all of which facilitate multiplex and live-cell
imaging. The IPC, which is funded by the ONPRC P51 core grant, provides comprehensive, expert, and cost-
effective advanced optical microscopy support to investigators by providing them access to state-of-the-art
microscopy technologies that enhance collaborative, multidisciplinary research. Acquisition of this instrument
will have a high impact on biomedical research at ONPRC and OHSU and will expand the scope of a wide
spectrum of NIH-funded projects. Numerous NIH-funded projects will heavily utilize the Stellaris 8 confocal
from all the ONPRC scientific divisions at ONPRC (Neuroscience, Pathobiology and Immunology,
Reproductive and Developmental Sciences, Genetics, and Cardiometabolic Health). The instrument will be
sited in the Advanced Optical Microscopy component of the IPC. ONPRC commits to ensuring long-term,
efficient use of the instrument by covering costs of the service contract and Core staff salary via the P51 grant
and as needed. Instrument time not used by the ONPRC investigators will be available to other scientists at
ONPRC's host institution, Oregon Health & Science University (OHSU), and collaborating biomedical research
entities. The introduction of this instrument will fulfill the growing needs of the biomedical research community
at ONPRC and OHSU to incorporate state-of-the-art confocal microscopy into their research.

## Key facts

- **NIH application ID:** 10600678
- **Project number:** 3P51OD011092-63S3
- **Recipient organization:** OREGON HEALTH & SCIENCE UNIVERSITY
- **Principal Investigator:** Peter Gordon Barr-Gillespie
- **Activity code:** P51 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $499,999
- **Award type:** 3
- **Project period:** 1997-05-01 → 2024-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10600678

## Citation

> US National Institutes of Health, RePORTER application 10600678, Upgrade of confocal microscopy at the Oregon National Primate Research Center (3P51OD011092-63S3). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10600678. Licensed CC0.

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