# Functionally Closed Purification and Elution of Untouched Cells using Cleavable Magnetic Beads with Digital Magnetic Sorting

> **NIH NIH R44** · FERROLOGIX, INC. · 2023 · $921,412

## Abstract

Project Summary
Isolation of specific and well-defined cell types to produce next generation cellular therapies remains a significant scale up
and scale out challenge for autologous and allogeneic therapies.
Through primary customer interviews of cell therapy developers, we learned there is an unmet need for scalable cell sorting
systems that can isolate rare cell types on multiple markers in production of nuanced cellular therapeutics. With preliminary
studies, we demonstrated that our scalable core technology (digital magnetic sorting) achieves superior rare cell isolation
and can achieve parallelized multitarget sorting to address this need.
In this proposal, we aim to develop a functionally closed, quantitative cell purification system that can isolate rare and
specific cell types based on multiple markers at throughputs conducive for cell therapy manufacturing.

## Key facts

- **NIH application ID:** 10603997
- **Project number:** 1R44GM149063-01
- **Recipient organization:** FERROLOGIX, INC.
- **Principal Investigator:** Coleman Murray
- **Activity code:** R44 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $921,412
- **Award type:** 1
- **Project period:** 2023-02-01 → 2025-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10603997

## Citation

> US National Institutes of Health, RePORTER application 10603997, Functionally Closed Purification and Elution of Untouched Cells using Cleavable Magnetic Beads with Digital Magnetic Sorting (1R44GM149063-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10603997. Licensed CC0.

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