PROJECT SUMMARY Pediatric dermatology is a relatively young specialty that has lacked robust data about the natural history and long-term outcomes of skin disorders that begin in infancy and childhood. In addition, evidence-based guidelines of care, standardized treatment protocols, and FDA-approved therapies for the majority of pediatric dermatologic disorders are sparse. The Pediatric Dermatology Research Alliance (PeDRA) was founded in 2012 to address these crucial yet unmet needs. PeDRA's primary mission is to create, inspire, and sustain research to prevent, treat, and cure childhood skin disease. The long-term goal of PeDRA is to leverage such research to improve the health outcomes of children with skin disorders. Annual conferences have been integral to the success of PeDRA, providing a forum for educating investigators, identifying and prioritizing research needs and opportunities, and developing and initiating innovative projects. A combination of didactic lectures, expert-led interactive discussions, skill-building workshops, panel and poster sessions, and disease- focused small-group sessions are the foundation of PeDRA's meetings. This proposal is for the 10th PeDRA Annual Conference, set to take place in November of 2022 with the following aims: 1) Provide education and engagement opportunities related to relevant research skills, building and leveraging community to advance science, and integrating equity, diversity, and inclusion across pediatric dermatology research; 2) Advance existing research projects and develop new research priorities within PeDRA's focus areas; and 3) Provide a forum for the dissemination of final and ongoing research results from a broad group of investigators to a diverse audience that includes patient stakeholders, industry representatives, and researchers from multiple fields including potential NIH collaborators. The expected outcomes of this meeting are a more developed set of research skills for current and future physician-scientists, enhanced productivity, strengthened networks, and the conduct of high-quality research. These activities will accelerate the pace of pediatric dermatology research, allowing clinicians to better understand, prevent and treat skin disease in children, and giving patients and families options to manage diseases and make informed treatment decisions.