# ISU VDL Ambient Ionization Equipment Proposal

> **NIH FDA U18** · IOWA STATE UNIVERSITY · 2022 · $33,680

## Abstract

2022 Vet-LIRN Grant for Ambient Ionization Equipment
Project Summary:
The purpose of this application is to purchase Coated Blade Spray (CBS) equipment for mass
spectrometry analysis. As analytical technologies improve it is essential for labs to have new
and improved analytical equipment. Coated Blade Spray mass spectrometry (CBS-MS) is an
approximately 8 year-old analytical technology that allows for the rapid analysis of several types
of samples in minutes. The Coated Blade Spray ionization source is interfaced directly with the
mass spectrometer and provides an ambient ionization platform for multiple sample types and
compounds. The time-consuming chromatography step of traditional liquid chromatography
mass spectrometry (LC-MS) analysis is eliminated with CBS-MS. The total analysis time for
samples with CBS-MS is under 2 minutes per sample. This new analytical technology would
greatly enhance the capacity of both the ISU VDL analytical laboratory and the Vet-LIRN
network.

## Key facts

- **NIH application ID:** 10610148
- **Project number:** 1U18FD007719-01
- **Recipient organization:** IOWA STATE UNIVERSITY
- **Principal Investigator:** Scott Louis Radke
- **Activity code:** U18 (R01, R21, SBIR, etc.)
- **Funding institute:** FDA
- **Fiscal year:** 2022
- **Award amount:** $33,680
- **Award type:** 1
- **Project period:** 2022-09-01 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10610148

## Citation

> US National Institutes of Health, RePORTER application 10610148, ISU VDL Ambient Ionization Equipment Proposal (1U18FD007719-01). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10610148. Licensed CC0.

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