# Latinx Hazardous Drinkers with Clinical Anxiety: Effectiveness Trial of a Personalized Normative Feedback Intervention

> **NIH NIH R01** · UNIVERSITY OF HOUSTON · 2022 · $43,229

## Abstract

1. Summary of Funded Grant
 Despite being one of the largest and fastest-growing demographics in the United States (US), Latinx
persons experience striking health disparities, particularly in terms of hazardous drinking and co-occurring
clinical anxiety. No interventions to date have targeted hazardous drinking in the context of clinical anxiety
among Latinx persons. The current R01 proposal builds upon our past work by developing a brief, single-
session, computer-based, personalized feedback intervention (PFI) designed to enhance knowledge regarding
adverse anxiety-alcohol interrelations, increase motivation and intention to reduce hazardous drinking, and
reduce positive attitudes and intentions regarding the use of alcohol for anxiety.
 Specifically, we propose to develop a low-cost, highly disseminatable, integrated PFI for Latinx
hazardous drinkers with clinical anxiety (AA-PFI 1.0) that will be implemented and tested for effectiveness in
community-based health clinics. Our approach will follow a staged model consistent with National Institutes of
Health (NIH) guidelines for developing and standardizing behavioral interventions. Phase IA activities will
involve collecting qualitative and quantitative feedback from three iterative focus groups (N = 21) to refine
intervention content and evaluate treatment acceptability and feasibility. Phase IB activities will include a
rigorous randomized clinical trial designed to compare the effectiveness of AA-PFI 2.0 to a control PFI (C-PFI)
among a sample of 250 Latinx hazardous drinkers with clinical anxiety who receive care within community-
based health clinics. This study represents an important and pivotal step in the larger landscape of translating
basic research to more efficacious strategies for reducing hazardous drinking in underserved populations with
biobehavioral comorbidities. The proposed research project supports the 2017-2021 strategic plan of the
National Institute on Alcohol Abuse and Alcoholism (NIAAA) by advancing research in two of the key areas.
First, the current proposal has the end goal of improving strategies to prevent alcohol misuse, alcohol use
disorder, and alcohol-related consequences among an ‘at-risk’ population for these conditions (goal 3).
Second, it enhances the public health impact of NIAAA-supported research by focusing on one of the fastest-
growing and largest demographics in the US who demonstrate disparities in hazardous drinking (goal 5). The
current application aligns with the goals of RFA-AA-21-001 by proposing to examine the effectiveness of a low
cost, highly disseminatable, personalized, culturally adapted PFI for Latinx hazardous drinkers with clinical
anxiety within community-based health clinics. Given the collective public health impact of concurrent anxiety
and alcohol use, we believe the proposed study will yield findings that enhance scientific knowledge, advance
our understanding of mechanisms in anxiety-alcohol use relations, and inform the deve...

## Key facts

- **NIH application ID:** 10616033
- **Project number:** 3R01AA029807-02S1
- **Recipient organization:** UNIVERSITY OF HOUSTON
- **Principal Investigator:** MICHAEL J. ZVOLENSKY
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $43,229
- **Award type:** 3
- **Project period:** 2021-09-20 → 2026-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10616033

## Citation

> US National Institutes of Health, RePORTER application 10616033, Latinx Hazardous Drinkers with Clinical Anxiety: Effectiveness Trial of a Personalized Normative Feedback Intervention (3R01AA029807-02S1). Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/grant/nih/10616033. Licensed CC0.

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