# Strategies to Innovate EmeRgENcy Care Clinical trials Network (SIREN) - Pittsburgh

> **NIH NIH U24** · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2022 · $82,422

## Abstract

Project Summary and Abstract
This supplement requests support of effort for key individuals that will allow the University of Pittsburgh site for
the Strategies to Innovate Emergency Care Clinical Trials Network (SIREN) to continue operations as a Hub
for recruiting participants into emergency care research. Uninterrupted support of the Hub will ensure
successful enrollment of participants into the following SIREN trials; ICECAP, BOOST-3, and Peds-ICECAP.
We will continue to support the ancillary studies for these trials: PRECICECAP, Bio-BOOST and electro-
BOOST. Our specific Aims remain: 1. Provide administrative structure to rapidly implement and enroll in
clinical trials of emergency treatments. 2. Minimize time, cost and regulatory barriers to multicenter clinical
trials in emergency settings. 3. Explore innovative strategies to increase identification, recruitment, and
consent in emergency treatment trials. 4. Explore innovative strategies to increase quality of emergency care
data and to ensure retention of subjects enrolled in emergency settings.

## Key facts

- **NIH application ID:** 10621443
- **Project number:** 3U24NS100656-05S1
- **Recipient organization:** UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- **Principal Investigator:** Clifton W. Callaway
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $82,422
- **Award type:** 3
- **Project period:** 2017-07-15 → 2023-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10621443

## Citation

> US National Institutes of Health, RePORTER application 10621443, Strategies to Innovate EmeRgENcy Care Clinical trials Network (SIREN) - Pittsburgh (3U24NS100656-05S1). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10621443. Licensed CC0.

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