Abstract: This application responds to PAR-20-094 and seeks renewed R25 support for MH101072, UCSD’s “Psych- iatry Residency Research Track” (RRT) to stimulate academic psychiatrists to conduct research into the causes and treatments of mental illness. This R25, first funded in 2013, was renewed in 2018 with a “10” priority score. In FY 6-9, 100% of the Residents who had “matched” into this RRT in FY1-5 graduated into “triple threat” positions: 6 are Faculty (5 with Career Development Awards plus significant private funding) and one is a PGY5 Fellow. Two “internal” trainees joined the RRT mid-Residency. Four of 9 RRT graduates to-date are from NIH-defined underrepresented groups. A Psychiatry Summer Research Fellowship (SPRF) for URM Medical Students, funded by this R25, successfully trained future URM Academic Psychiatrists. This renewal application builds on the strengths of FY1-9 and the scientific expertise of UCSD faculty to sustain an RRT that is both substantive and innovative. In FY11-15, MH101072 will achieve the goals of the NIMH Council report, “Investing in the Future,” and of this FOA by expanding the pool of diverse Psychiatric researchers - a key step towards improving treatment and outcome for mental disorders. This application will achieve 2 Specific Aims: Aim 1. To recruit and educate the highest caliber future psychiatric researchers. Trainees complete a 4-year RRT; protected research time rises from 17% (PGY2) to 40% (PGY3) to 70% (PGY4), though core programs effectively extend these percentages. PGY3-4 seminars provide solid grounding in research design, data analysis, manuscript preparation and responsible conduct of research. Trainees learn academic survival skills and receive thoughtful supervision and personalized career mentorship. The core curriculum, detailed in this application, strengthens and sustains trainees' career connection with mental health research and the core missions of the NIMH. In FY11-15, innovative changes will solidify trainee research funding, build vertical cohesiveness across the RRT and engage RRT graduates in early career mentorship activities. Aim 2. To increase the number of research psychiatrists from underrepresented backgrounds. Diversity among RRT graduates grew from 0% in the 10 years prior to this R25, to 44.4% in the past cycle; diversity recruitment will expand in FY11-15. The SPRF for URM medical students added 6 URM trainees to Psychiatry Residencies, including 2 to RRT’s; 2 more SPRF trainees still in med school are headed into Psychiatry. This renewal builds on this success by doubling the size of our SPRF to 4 trainees per Summer. With renewed support, MH101072 will admit 10 new RRT trainees, graduate 9 trainees (5 current + 4 new), leaving 8 trainees “in the pipeline” to complete their training via renewed R25 or DoP support. This will bring the total yield of MH101072 (FY1-15) to 30 RRT graduates, in addition to 36 URM Summer Fellows. This RRT will provide individualized ove...