# Administrative supplement to Duke G20 award

> **NIH NIH G20** · DUKE UNIVERSITY · 2022 · $3,264,761

## Abstract

Project Summary/Abstract:
The Duke Regional Biocontainment Laboratory (RBL) was constructed with funding from the National Institutes
of Health (NIH) to support basic research necessary to develop drugs, diagnostics, and vaccines for
emerging/reemerging infections and biodefense. The state-of-the-art biocontainment facility, designed to
support lab and small animal research, was fully commissioned and opened for operation in 2007 on the Duke
University Medical School Campus in Durham, NC. The Duke RBL facility supports grant/contract-funded
investigators and also provides biocontainment labs, innovative host monitoring assays and small animal models
through Core Service Center Units on a cost recovery basis. Fourteen years of use and time have rendered
some of the Duke RBL facilities, systems and critical core research equipment obsolete, or in need of repair,
replacement or modernization. Since award of the parent G20 we have identified additional critical deﬁciencies
of the facility’s existing physical infrastructure that limit biosafety, security or threaten the provision of services it
offers and research-related activities it supports. We will address these additional deficiencies through this
supplement funding in our three original Specific Aims: 1) Modernize Building Control Systems – Replace and
upgrade obsolete air compressor and the BACNet (Building Automation Control Network); 2) Modernize
Biosafety and Security Systems - Replace aged/damaged PAPR units; and 3) Modernize Research Resources
– Replace or add additional major equipment to the Duke RBL Research Service Cores - liquid handling
automation equipment, ELISpot reader, next-generation Luminex reader, upgraded cell counter, replacement
incubators, freezers and centrifuges, advanced fluorescence microscopy capability in BSL3, additional Allentown
Biocontainment mouse caging, and live animal imaging with micro CT capability. These Aims/Goals will be
accomplished by the highly integrated project management team assembled in the parent award with solid
institutional support and trusted contractors/vendors that were part of the original design and construction of the
facility.

## Key facts

- **NIH application ID:** 10626469
- **Project number:** 3G20AI167200-01S1
- **Recipient organization:** DUKE UNIVERSITY
- **Principal Investigator:** Herman F Staats
- **Activity code:** G20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $3,264,761
- **Award type:** 3
- **Project period:** 2021-09-23 → 2025-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10626469

## Citation

> US National Institutes of Health, RePORTER application 10626469, Administrative supplement to Duke G20 award (3G20AI167200-01S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10626469. Licensed CC0.

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