Project Summary/Abstract Title: Examining misinformation correction strategies to encourage clinical trial participation amongst Black Americans. In order to contribute to clinical trial diversity, this research seeks to address clinical trial disparities in the Black community by focusing on the misinformation swirling on social media. This ethnic group has historically been the target and victim of unethical medical experiments, most notably the Tuskegee Experiment in the US. Some argue that Black individuals’ mistrust of clinical trials stems from the fear that medical research will cause sterilization, and the association between this misconception and clinical trials is based on the historical trauma that the Black community experienced in the past. Black people are still concerned about medical abuse and skeptical of the health care system. Psychological barriers such as fear and mistrust easily invite misconceptions, which will then prevent individuals from making a reasonable decision. When it comes to health-related misinformation, this is even more problematic, putting public health in danger. Extant research, however, only rarely discusses how to address misinformation to increase enrollment in clinical trials. To address the gaps in the literature, the current research project proposes two experiments to find ways (1) to strategically debunk and counter misconceptions by dissociating historical trauma and medical research using corrective interventions and (2) to seek ways to partner with same-race doctor influencers on social media to effectively deliver the message to the Black population. The first experiment will test how the factual elaboration debunking strategy will affect willingness to participate in clinical research through enhanced perceived social norms, self-efficacy, and attitudes in order to understand the role of corrective intervention in decision-making. The second experiment will test how same-race doctor influencers might effectively deliver the corrective intervention and strengthen sense of community to increase intention to participate in clinical trials. Therefore, this research project aims to contribute to both clinical trial research and health care professionals’ knowledge of how to tackle psychological barriers derived from historical trauma and how to better communicate about clinical trials in a more relatable and accessible manner to increase enrollment in clinical trials by Black Americans.