# Timeliness of Management of Trauma Related Hemorrhage and Trauma Related Coagulopathy

> **NIH NIH K23** · NORTHWESTERN UNIVERSITY · 2023 · $185,332

## Abstract

PROJECT SUMMARY
Injury is the most common cause of death in people younger than 46 years of age, and bleeding after injury is
the most common cause of preventable death. Treatment of bleeding requires timely procedures to stop the
bleeding as well as medications and blood transfusions to prevent blood thinning. Hospitals that specialize in
treating injury have protocols, medications, devices and clinical staff available 24 hours a day and seven days
a week. Injured people treated at specialized hospitals are more likely to live. However, there are far too many
injured people every year than can be treated at specialized hospitals so minor injuries are cared for at
hospitals not specialized in treating injuries. Severely injured people are taken to hospitals not specialized in
treating injuries when specialized hospitals are too far away, or the emergency medical personnel
underestimate how seriously injured someone is. Hospitals not specialized in treating injuries do not participate
in ongoing injury clinical trials, regional data registries nor national quality improvement programs, and as a
result what happens there that leads to people bleeding to death is unknown. This application's long-term
objective is to improve the timeliness of treatment of bleeding after injury. The Specific Aims will be to: 1)
understand how bleeding after injury is managed in hospitals that do and do not specialize in treating injuries;
2) identify the reasons patients do not get timely treatment; and3) determine how to improve the timeliness of
treatment. The central hypothesis is that treatment of bleeding is not standardized in hospitals not specialized
in treating injuries and leads to a delay in transferring injured people to specialized hospitals. Identifying
modifiable healthcare system, hospital, and patient factors can inform the design of a systematic process to
quickly temporarily stabalize bleeding of injured people initially at non-specialized centers then expedite
transfer to specialized hospitals by engaging key stakeholders from across the spectrum of hospitals. This will
ensure that people who are bleeding after injury are cared for at the right place at the right time. Ultimately, the
right treatment at the right time will give people initially taken to hospitals not specialized in treating injuries the
same chance at life as those taken to specialized hospitals. As a Career Development Award, the proposed
training plan will include training in data science, systems engineering and design. The methods to be learned
and employed will be machine learning, failure mode, effects and criticality analysis and user-centered design.
The health relatedness of the project is to understand current practice management of bleeding after injury, in
order to improve the timeliness of bleeding treatments to enhance the health of injured inviduals.

## Key facts

- **NIH application ID:** 10641870
- **Project number:** 5K23HL157832-03
- **Recipient organization:** NORTHWESTERN UNIVERSITY
- **Principal Investigator:** Anne M Stey
- **Activity code:** K23 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2023
- **Award amount:** $185,332
- **Award type:** 5
- **Project period:** 2021-06-01 → 2026-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10641870

## Citation

> US National Institutes of Health, RePORTER application 10641870, Timeliness of Management of Trauma Related Hemorrhage and Trauma Related Coagulopathy (5K23HL157832-03). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10641870. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*