# Health Promotion and Disease Prevention Research Centers

> **NIH ALLCDC U48** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2023 · $1,345,000

## Abstract

Abstract
To respond to the HIV epidemic and reduce health disparities in HIV incidence and outcomes, we propose a
Prevention Research Center (PRC) at the University of California, San Francisco (UCSF) that facilitates
significant and innovative health science research through partnerships with public health colleagues that
ultimately improves public health. The HIV epidemic continues to be a major public health crisis in the U.S.,
with more than 1 million people living with HIV and more than 50,000 becoming newly infected every year.
Given the progress in preventing and treating HIV, the Centers for Disease Control and Prevention (CDC) has
identified HIV as a winnable battle, Healthy People 2020 has included HIV as a topic area, sexual health is part
of the National Prevention Strategy, and United States has released the National HIV/AIDS Strategy. HIV has
had a disproportionate impact on African Americans and transgender women, representing one of the largest
health disparities in the U.S. While comprising just 13% of the total national population, African Americans
account for 51% of all new HIV/AIDS diagnoses. The rate of new HIV infections is particularly profound for
transgender women. About a quarter (22-28%) of transgender women are living with HIV, representing 34
times the odds of infection compared to the general population. More than half (about 56%) of African
American transgender women are living with HIV. These data highlight the urgent need to focus research on
eliminating HIV health disparities among African Americans in general and transgender women in particular.
This application proposes to develop and implement authentic community engagement and a support
implementation research project that focuses prevention HIV by linking, engaging and reengaging in care
transgender women living with HIV. Our overall aims are to:
1. Maintain the multi-disciplinary UCSF PRC to catalyze high-quality applied health promotion and HIV
prevention research;
2. Increase availability of evidence-based strategies, interventions, and implementation tools and facilitate
innovative, high-impact, multidisciplinary HIV research and knowledge dissemination to address the HIV
epidemic;
3. Develop and maximize the public health impact of optimally efficacious, culturally responsive, and
implementable interventions, strategies, and prevention tools by moving them into policy and practice;
4. To conduct an applied public health prevention research project, using a community engaged approach, that
addresses the significant health disparity in HIV among transgender women; and
The PRC will include an administrative infrastructure, a community partnerships core, a dissemination and
translation core, and an evaluation core. The work of the cores will be leveraged to reduce significant HIV-
related health disparities and strengthen public health programs and practice.

## Key facts

- **NIH application ID:** 10650197
- **Project number:** 5U48DP006374-05
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** GREGORY Michael REBCHOOK
- **Activity code:** U48 (R01, R21, SBIR, etc.)
- **Funding institute:** ALLCDC
- **Fiscal year:** 2023
- **Award amount:** $1,345,000
- **Award type:** 5
- **Project period:** 2019-09-30 → 2024-09-29

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10650197

## Citation

> US National Institutes of Health, RePORTER application 10650197, Health Promotion and Disease Prevention Research Centers (5U48DP006374-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10650197. Licensed CC0.

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