# Association Study of Orofacial Cleft Risk Variants across All of Us Cancer Diagnoses

> **NIH NIH R03** · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2022 · $118,105

## Abstract

ABSTRACT
This new grant is a Revision/Administrative Supplement to parent grant R03-DE032062. It has long been noted
that individuals with orofacial clefts (OFCs) and their unaffected relatives have a higher risk of certain
cancers. The hypothesis of this revision is that the association between OFC and cancer is in part due to
genetic commonalities. In this Revision, we will investigate possible associations between OFC genetic risk
variants with the cancer diagnoses in All of Us.

## Key facts

- **NIH application ID:** 10654330
- **Project number:** 3R03DE032062-01S1
- **Recipient organization:** UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- **Principal Investigator:** Mary L. Marazita
- **Activity code:** R03 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $118,105
- **Award type:** 3
- **Project period:** 2022-08-15 → 2023-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10654330

## Citation

> US National Institutes of Health, RePORTER application 10654330, Association Study of Orofacial Cleft Risk Variants across All of Us Cancer Diagnoses (3R03DE032062-01S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10654330. Licensed CC0.

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