# Center for Population Health and Aging

> **NIH NIH P30** · DUKE UNIVERSITY · 2022 · $370,180

## Abstract

Abstract/Summary: We propose an administrative supplement to enhance the existing longitudinal
Dunedin Study with, per NOSI-AG-22-022, “new exposure measures and mechanisms linking exposures
to AD/ADRD outcomes.” The NOSI calls for new research infrastructure that “addresses the role of
diverse physical, chemical, social, psychological, and economic exposures across multiple levels and
across the life course in the etiology and social disparities” of AD/ADRD. The Dunedin Study, now in its
5th decade, has led the field in tracking social, psychological, and economic exposures since our cohort’s
birth in 1972, using multidisciplinary methods spanning sociology, psychology, medicine, dentistry,
sensory science, and economics. Here we propose to collect chemical and physical exposure data at
Dunedin Phase 52. Doing so will make the Study one of the world’s first truly “exposomic” investigations
of life-course brain aging and AD/ADRD risk. We propose to measure toxic metals, home environmental
quality, and neighborhood environmental quality.

## Key facts

- **NIH application ID:** 10661129
- **Project number:** 3P30AG034424-13S1
- **Recipient organization:** DUKE UNIVERSITY
- **Principal Investigator:** SCOTT M. LYNCH
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $370,180
- **Award type:** 3
- **Project period:** 2009-07-15 → 2025-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10661129

## Citation

> US National Institutes of Health, RePORTER application 10661129, Center for Population Health and Aging (3P30AG034424-13S1). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10661129. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*