# Topological Mapping of Immune, Microbiota, Metabolomic and Clinical Phenotypes to Reveal ME/CFS Disease Mechanisms - Admin Core

> **NIH NIH U54** · JACKSON LABORATORY · 2022 · $45,400

## Abstract

PROJECT SUMMARY ADMINISTRATIVE CORE
The goal of the Administrative (Admin) Core is to provide management, oversight and logistical support for
the proposed JAX Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Collaborative Research Center
(ME/CFS CRC). The Admin Core's role will be to: 1) foster productive scientific interactions within the JAX
ME/CFS CRC, which involves 12 investigators at four different locations (JAX, University of Connecticut,
North Carolina State University, Bateman Horne Center); 2) maintain alignment of the JAX ME/CFS CRC
with ME/CFS Network activities; 3) monitor the progress of research projects, collaborative projects, and
cores towards their specific research and resource-sharing goals; 4) ensure efficient data sharing with the
ME/CFS Data Management and Coordinating Center (DMCC); 5) coordinate career development and
community outreach activities; and 6) administer the solicitation, review, and selection of Collaborative
Project proposals. The Admin Core will be led by Center Director Dr. Derya Unutmaz, a highly accomplished
immunologist with experience in Center leadership and a deep connection to the ME/CFS community. Dr.
Unutmaz recently formed a clinical alliance withthe Bateman Horne Center of Excellence, the clinical partner
on this application, to study ME/CFS. Dr. Unutmaz will leverage this connection with the BHC and with the
proposed Community Impact Steering Committee as a source of feedback from key stakeholders as well as an
outlet for dissemination of ME/CFS research.
The Admin Core will
leverage the excellent capabilities, facilities
and resources offered at JAX for administering large-scale collaborative research projects and educational
activities. These resources include support for a full time, institutionally supported Center Administrator, who will
assist Dr. Unutmaz by performing many essential Center functions.
Together,
Dr. Unutmaz and the Center
Administrator will effectively execute the following Specific Aims: 1) Optimize integration and function of JAX
ME/CFS CRC activities through strong administrative and scientific oversight, including strategic planning,
budgetary oversight, conflict resolution, executive decisions on the direction of research activities and
collaborations with other ME/CFS Centers; 2) Enhance communication and collaboration among JAX ME/CFS
CRC investigators and between ME/CFS centers and NIH representatives; and 3) Convene Community Impact
Steering Committee and engage in education and outreach activities for ME/CFS patients, physicians, and
investigators new to ME/CFS research.

## Key facts

- **NIH application ID:** 10664153
- **Project number:** 3U54NS105539-05S1
- **Recipient organization:** JACKSON LABORATORY
- **Principal Investigator:** Derya Unutmaz
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $45,400
- **Award type:** 3
- **Project period:** 2022-07-01 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10664153

## Citation

> US National Institutes of Health, RePORTER application 10664153, Topological Mapping of Immune, Microbiota, Metabolomic and Clinical Phenotypes to Reveal ME/CFS Disease Mechanisms - Admin Core (3U54NS105539-05S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10664153. Licensed CC0.

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