PROGRAM SUMMARY/ABSTRACT T32DA013911, HIV and Other Infectious Consequences of Substance Abuse, has been training fellows for over 20 years. The training program entered a no-cost extension period on July 1, 2022 as we now await the disposition of our competitive renewal application submitted earlier this year. This supplement requests support for three one-year training slots to support exceptional post-doctoral research fellows. The overall theme of the parent training program is community-engaged clinical research on HIV and other infectious diseases within the context of the substance use epidemic. One of the most important strengths of this program is its into a trans-disciplinary collaboration between substance use science, HIV medicine and other infectious diseases (Hepatitis B/C, STDs, and TB), other medical disciplines, behavioral sciences, and epidemiology, and biostatistics. We have three exceptional scholars, two of whom are currently engaged in their first year of this training program.