# A Pilot for Enhancing Support for a Federated Framework of Biospecimens for Down Syndrome Research via the INCLUDE Data Hub

> **NIH NIH U2C** · CHILDREN'S HOSP OF PHILADELPHIA · 2022 · $399,870

## Abstract

PROJECT SUMMARY
Under the proposed pilot, the respective biorepositories of the Children’s Hospital of Philadelphia and the Crnic
Institute Human Trisome Project Biobank will partner with the INCLUDE Data Hub to define and implement the
required workflows and tools to support biosample-based data/meta data integration. Such efforts will empower
portal users to engage cohort creation and biosample use frameworks via the INCLUDE Data Hub and their
downstream interactions with repositories as a combination of centralized and federated resources.

## Key facts

- **NIH application ID:** 10671310
- **Project number:** 3U2CHL156291-03S1
- **Recipient organization:** CHILDREN'S HOSP OF PHILADELPHIA
- **Principal Investigator:** Joaquin M. Espinosa
- **Activity code:** U2C (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $399,870
- **Award type:** 3
- **Project period:** 2020-09-26 → 2025-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10671310

## Citation

> US National Institutes of Health, RePORTER application 10671310, A Pilot for Enhancing Support for a Federated Framework of Biospecimens for Down Syndrome Research via the INCLUDE Data Hub (3U2CHL156291-03S1). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10671310. Licensed CC0.

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