# Understanding HIV/STD Risk and Enhancing PrEP Implementation Messaging in a Diverse Community-Based Sample of Gay, Bisexual, and Other Men Who Have Sex with Men in a Transformational Era

> **NIH ALLCDC U01** · EMORY UNIVERSITY · 2023 · $1,475,000

## Abstract

Abstract
The prevention of HIV in the United States is in a transformational era. In just a decade since the first finding of
efficacy for daily oral PrEP, there is a proliferation of new PrEP agents, including long-acting injectable PrEP,
and regimens, including “event-driven” (also called 2-1-1) PrEP. There has also been new knowledge about the
impact of antiretrovirals (ARVs) for treatment of HIV, and an emergent understanding that people living with HIV
who take ARVs and maintain a suppressed viral load are incapable of transmitting HIV to their sexual partners.
In this context, the idea of “protected” sex – which historically meant sex protected by condoms – has become
much more complex. To understand men’s preferences for prevention products and strategies and what choices
are being made by men with varying risk profiles, we will enroll a prospective cohort of 1275 of men who have
sex with men (MSM) in Atlanta, Detroit and San Diego and follow the cohort for two years. Each participant will
have 8 quarterly quantitative assessments, including discreet choice experiments; a subset of MSM will be
engaged in a qualitative assessments (focus group discussions and individual in-depth interviews) to help with
message development and refinement. HIV and STI testing will be provided in alternating 6-month windows.
Rapid reporting of results will produce actionable reports following each assessment wave. This project will
serve as a dynamic source of data about the evolving patterns of use and preference for PrEP among MSM.

## Key facts

- **NIH application ID:** 10671594
- **Project number:** 5U01PS005244-02
- **Recipient organization:** EMORY UNIVERSITY
- **Principal Investigator:** Patrick Sean Sullivan
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** ALLCDC
- **Fiscal year:** 2023
- **Award amount:** $1,475,000
- **Award type:** 5
- **Project period:** 2022-08-01 → 2026-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10671594

## Citation

> US National Institutes of Health, RePORTER application 10671594, Understanding HIV/STD Risk and Enhancing PrEP Implementation Messaging in a Diverse Community-Based Sample of Gay, Bisexual, and Other Men Who Have Sex with Men in a Transformational Era (5U01PS005244-02). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10671594. Licensed CC0.

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