# Pathology Peer Review and Pathology Support for the DNTP and DIR at NIEHS (EPL)

> **NIH NIH N01** · EXPERIMENTAL PATHOLOGY LABORATORIES · 2022 · $2,200,000

## Abstract

The subject contract was established to provide a broad range of routine and specialized pathology services in support of studies conducted under contract by the National Toxicology Program (NTP) and for supplemental studies on pathology specimens generated through these studies. The contract also provides critical pathology (including molecular pathology) support for studies conducted by in-house investigators at NIEHS and other NIEHS contract studies. Specifically, the following services are supported by this contract: 1) necropsy and in-house necropsy assistance; 2) histology (tissue trimming and processing, slide preparation, and staining); 3) histopathological evaluation/interpretation; 4) application of specialized qualitative and quantitative morphological procedures (immunohistochemistry, morphometrics, cell proliferation, apoptosis, electron microscopy); 5) adaptation, development, refinement, application of new techniques in cellular and molecular biology including (but not limited to) genotyping, DNA sequencing, in situ hybridization, DNA and RNA isolation and amplification, and real time, quantitative, and in situ PCR, as well as training in the application of these techniques; 6) Pathology Peer Review (including Pathology Data Review [PDR], Audit of Pathology Specimens [APS], Quality Assessment of pathology evaluations and Pathology Working Group Coordination [QA/PWG]) and technical support for these activities; 7) pathology data entry; 8) presentation or publication of pathology data or techniques, or support for these activities; 9) on-site pathology support, and 10) support for the clinical pathology group (data review, data archiving). The following work was completed for the National Toxicology Program and the NIEHS on this contract in the past year: six QA/PWGs; 2 APS reviews, 1 necropsy, 2 histology projects, pathological evaluation of 6 studies for in-house NIEHS projects, preparation of 6 posters or journal publications. In addition, there are many other projects for the NTP and NIEHS that are in progress. The on-site pathologists have participated in numerous PWGs and oversaw the pathology peer review for numerous studies. One has contributed to the to the NTP Nonneoplastic Lesion Atlas, and one has lead or contributed to numerous molecular pathology projects. For the clinical pathology group, quality control review or data archiving has been performed for 216 studies. The person performing this work also supports NTP in the data coordination unit and manages data for numerous NTP projects.

## Key facts

- **NIH application ID:** 10672872
- **Project number:** 273201500014C-P00016-9999-1
- **Recipient organization:** EXPERIMENTAL PATHOLOGY LABORATORIES
- **Principal Investigator:** RODNEY MILLER
- **Activity code:** N01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $2,200,000
- **Award type:** —
- **Project period:** 2015-07-28 → 2023-07-27

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10672872

## Citation

> US National Institutes of Health, RePORTER application 10672872, Pathology Peer Review and Pathology Support for the DNTP and DIR at NIEHS (EPL) (273201500014C-P00016-9999-1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10672872. Licensed CC0.

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