ABSTRACT The National Covid Cohort Collaborative (N3C), created by the National Center for Advancing Translational Sciences (NCATS) and the National Center for Data to Health (Cd2H) have created a centralized national database and analytic platform for scientists to use to study COVID-19 and identify potential treatments. It is a partnership among 75 institutions that is funded by the National Institutes of Health. Collaborators have contributed data so far on nearly 6 million COVID-19 positive patients, as well as several million control patients who tested negative for COVID-19. The collaborators use the clinical data on these patients to answer critical research questions to address the pandemic and accelerate development of effective treatments. The Northern New England Clinical and Translational Research Network has actively participated in N3C for over 2 years and is submitting this administrative supplement to allow for our continued participation for another year. This application details our past accomplishments and describes our planned work for the coming year.