PROJECT SUMMARY For this administrative supplement to our K12 BIRCWH grant, UC Davis is requesting support to add a fourth Scholar to our program for two years. We will train a Scholar of Vietnamese descent whose background meets the NIH criteria for being from an underrepresented minority group and disadvantaged background in interdisciplinary women’s health and sex differences research. This proposed Scholar is within 6 years of a terminal degree and will engage in interdisciplinary women’s health and/or sex/gender disparities, team science-based research and create an independent development plan for her pathway to independence. Her research focus will be cancer prevention in women through implementation science and will fit well into our BIRCWH crosscutting themes: 1) a lifespan approach to understanding normal development, illness/disease, and aging; 2) sex and gender determinants; 3) health disparities; and 4) interdisciplinary research. Over the past 17 years, the UC Davis BIRCWH program has trained a sizeable, diverse cadre of interdisciplinary researchers in women’s health and sex differences and heightened the visibility and prominence of this research. We will build on this strong foundation to create a next-generation BIRCWH program, led by PI, Dr. Nancy Lane, that increases its innovation and impact. We aim to foster an academically stimulating and nurturing environment for researchers in women’s health and sex differences, to facilitate their career development and encourage paradigm-shifting, interdisciplinary collaboration, and team science to advance research in women’s health and sex disparities. Our short-term BIRCWH objectives are to: 1) provide in-depth, individualized training and team-based interdisciplinary mentoring to support the independent career development of Scholars in interdisciplinary women’s health and sex differences research; and 2) advance and achieve high- impact women’s health and sex/gender differences research by establishing cross-disciplinary collaborations with UC Davis schools that advance science and health. Our long-term objectives are to: 1) improve women’s health by enhancing understanding of the unique aspects of female sex and gender and translating this knowledge to clinical practice; 2) develop transformative interdisciplinary team science for women’s health and sex/ gender disparities research; and 3) train leaders in interdisciplinary women’s health and sex differences research. To accomplish our objectives, our proposed new BIRCWH Scholar will participate in: 1) team- based, interdisciplinary mentored research and career development activities; 2) core courses on study design, grant writing, biostatistics, communication, team science and responsible conduct of research; 3) supplemental courses tailored to each Scholars’ needs and interests; 4) team-based interdisciplinary research; 5) integrated journal clubs; 6) monthly breakfast meetings with the PI and RD to discuss research and career p...